On admission

Discharge from hospital

Vc (n = 24)

no Vc (n = 74)

P value

Vc (n = 24)

no Vc (n = 74)

P value

Oxygenation index (mmHg)

424 (165.0)

443 (118.5)

0.63

471 (132)

410 (224)

0.46

Lactate (mmol/L)

1.75 (0.78)

1.8 (0.95)

0.78

1.6 (1.35)

1.8 (1.1)

0.94

White-cell count (× 109/L)

5.4 (2.4)

5.4 (2.15)

0.85

5.9 (2.55)

5.7 (3.2)

0.73

Lymphocyte count (× 109/L)

66.8 (12.93)

65.4 (16.4)

0.58

26.4 (9.35)

22.9 (10.6)

0.76

Neutrophil count (× 109/L)

24.65 (11.4)

25.9 (13.35)

0.65

62.4 (10.75)

64.6 (51.6)

0.97

Platelet count (× 109/L)

213 (97.5)

204 (67)

0.96

245 (105)

258 (148)

1.0

Alanine aminotransferase (U/liter)

17 (14.75)

21 (20.5)

0.18

20 (14.5)

26 (17.0)

0.10

Aspartate aminotransferase (U/liter)

20.5 (7.75)

24 (11.0)

0.11

19 (6.5)

22 (7.0)

0.081

Total bilirubin (μmol/L)

14.05 (11.13)

13.1 (9.25)

0.87

13.4 (6.7)

12.2 (5.7)

0.63

Direct bilirubin (μmol/L)

5.2 (3.45)

4.8 (3.7)

0.96

3.9 (1.75)

3.8 (2.0)

0.96

Indirect bilirubin (μmol/L)

8.5 (7.58)

8.2 (5.4)

0.86

9.7 (5.2)

8.5 (4.2)

0.57

Uric acid (μmol/L)

252 (94)

266 (152.5)

0.47

282 (85)

267 (116)

0.86

Creatinine (μmol/L)

75.5 (25.75)

76 (21)

0.90

76 (16.5)

74 (20)

0.92

Blood urea nitrogen (mmol/L)

3.96 (1.58)

4.19 (1.82)

0.87

3.69 (1.69)

3.6 (1.83)

0.77

Creatinine clearance rate (ml/min)

103 (23.25)

95 (23.5)

0.32

101 (23.5)

95 (27)

0.42

HLOS (d)

12 (12.5)

16 (11)

0.28

Clinic course (d)

19 (12.5)

21 (9)

0.92