| On admission |
|
| At the lowest oxygenation index time | Discharge from hospital |
|
| |||
| Moderate case | Severe case | P Value | Moderate case | Severe case | P Value | Moderate case | Severe case | P Valuea | P Valueb |
Oxygenation index (mmHg) | 452 (105) | 329 (149.5) | 0.000 | 452 (121.75) | 234 (72) | 0.000 | 481.5 (273) | 374 (98.5) | 0.002 | 0.000 |
Lactate (mmol/L) | 1.75 (0.85) | 1.9 (0.9) | 0.88 | 1.7 (0.68) | 1.95 (1.32) | 0.040 | 1.7 (1.07) | 1.7 (1.22) | 0.388 | 0.54 |
White-cell count (×109/L) | 5.3 (2.05) | 5.5 (3.75) | 0.79 | 6.0 (2.05) | 8.05 (4.93) | 0.006 | 6.0 (1.7) | 6.95 (3.83) | 0.000 | 0.21 |
Lymphocyte ratio (%) | 25.75 (9.8) | 23.6 (20.85) | 0.041 | 25.5 (13.95) | 11.55 (15.58) | 0.000 | 25.3 (9.03) | 19.9 (15.75) | 0.459 | 0.000 |
Neutrophil ratio (%) | 65 (14.43) | 66.1 (27.25) | 0.039 | 66.1 (16.12) | 81.25 (21.8) | 0.000 | 62.85 (11.9) | 66.3 (15.38) | 0.002 | 0.000 |
Platelet count (×109/L) | 209 (62.5) | 185 (128.5) | 0.23 | 217.5 (73.25) | 230.5 (111.25) | 0.57 | 270 (100.5) | 205.5 (100.25) | 0.003 | 0.001 |
Alanine aminotransferase (U/liter) | 18 (17.75) | 30 (24) | 0.032 | 18 (17) | 28 (20.25) | 0.005 | 20.5 (22.5) | 26.5 (15.5) | 0.136 | 0.27 |
Aspartate aminotransferase (U/liter) | 22 (8.0) | 31 (23.5) | 0.001 | 24 (8.5) | 23.5 (16.0) | 0.29 | 21.0 (7) | 22.0 (6) | 0.989 | 0.053 |
Total bilirubin (μmol/L) | 13.15 (9.42) | 15.3 (13.55) | 0.51 | 14.4 (7.18) | 16.1 (15.4) | 0.95 | 12.7 (4.78) | 11.8 (7.55) | 0.122 | 0.28 |
Direct bilirubin (μmol/L) | 4.85 (3.38) | 6.2 (5.6) | 0.25 | 5.35 (2.45) | 6.25 (6.10) | 0.68 | 3.95 (1.5) | 3.0 (2.6) | 0.024 | 0.001 |
Indirect bilirubin (μmol/L) | 8.15 (5.85) | 9.1 (7.6) | 0.67 | 9.0 (5.5) | 10.20 (7.78) | 0.90 | 8.7 (3.93) | 8.15 (5.02) | 0.239 | 0.91 |
Uric acid (μmol/L) | 266 (128.75) | 252 (170.5) | 0.23 | 257 (139.5) | 224 (128) | 0.028 | 273 (116) | 269.5 (95.25) | 0.040 | 0.29 |
Creatinine (μmol/L) | 77 (22) | 73 (21) | 0.77 | 78 (20) | 73 (23.75) | 0.38 | 76.5 (21.25) | 69 (17.5) | 0.242 | 0.036 |
Blood urea nitrogen (mmol/L) | 4.18 (1.7) | 4.19 (1.74) | 0.55 | 3.84 (1.23) | 5.03 (3.6) | 0.044 | 3.41 (1.72) | 3.78 (1.7) | 0.023 | 0.53 |
Creatinine clearance rate (ml/min) | 101.5 (22) | 86 (19.5) | 0.003 | 102 (15.75) | 86 (18) | 0.021 | 103.5 (28.75) | 92 (18.5) | 0.135 | 0.52 |