Number of patients

Patient characteristics

CIAKI incidence, %

Marker capture time, h

Conclusion

Statistics

Authors

100

GFR > 60 ml,

Age 63.2 ± 12.0 yrs.

11%

0, 2, 4, 8, 24

Significant NGAL increase in 2 hours

Serum NGAL increase in 2 hours (p < 0.05), in 4 h (p < 0.01), in 8 hours (p < 0.05), urine NGAL increase in 4 hours (p < 0.05), in 8 hours (p < 0.001), in 12 hours (p < 0.05)

[45]

140

DM/non-DM, GFR > 60 ml,

Age 63.8 ± 11.4 yrs.

14% (DM)

10% (non-DM)

0, 2, 4, 8, 24

Significant NGAL increase in both cohorts, more significant in DM cohort

p < 0.05 for both cohorts vs marker level before CM administration, p < 0.001 for DM vs non-DM cohort

[46]

25

non-DM, GFR > 60 ml, Age 64.3 ± 9.8 yrs.

0%

0, 2, 4, 12

No CIAKI. Significant NGAL increase in 2 hours

Serum NGAL increase in 2 hours (p < 0.05), in 4 hours (p < 0.01), urine NGAL increase in 4 and 12 hours (p < 0.05)

[47]

150

GFR > 60 ml,

Age 66.3 ± 9.9 yrs.

8.7%

0.24

Significant NGAL increase during first 24 hours

p < 0.05 vs. control group

[48]

208

DM + GFR > 60 ml, Age 70.8 ± 8.5 yrs.

18.8%

0, 2, 4, 12 - 24

Significant NGAL increase already in 2 hours

p = 0.03 (2 hours), p = 0.007 (4 hours), p = 0.0015 (12 - 24 hours)

[49]