Variable | Newly diagnosed N = 55 | On treatment N = 30 | Stop treatment N = 39 | Healthy N = 26 | P value |
EF |
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Mean ± SD | 44.65 ± 7.52 | 41.7 ± 7.97 | 42.67 ± 6.82 | 64.5 ± 4.81 | <0.0001 |
Mean (range) | 44 (28 - 58) | 43 (25 - 55) | 42 (22 - 55) | 65 (57 - 72) |
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P1 = 0.40, P2 = 1.00, P3 < 0.0001, P4 = 1.00, P5 < 0.0001, P6 < 0.0001 | |||||
Degree of EF |
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Preserved EF | 4 (7.27%) | 0 (0.00%) | 0 (0.00%) | 19 (73.08%) | <0.0001 |
Mid-range EF | 18 (32.73%) | 11 (36.67%) | 12 (30.77%) | 7 (26.92%) |
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Reduced EF | 33 (60.00%) | 19 (63.33%) | 27 (69.23%) | 0 |
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P1 = 0.32, P2 = 0.21, P3 < 0.0001, P4 = 0.61, P5 < 0.0001, P6 < 0.0001 | |||||
NYHA Class |
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No dyspnea | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) | 26 (100%) |
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Dyspnea with extra effort | 0 (0.00%) | 0 (0.00%) | 0 (0.00%) | 0 | <0.0001 |
Dyspnea with normal effort | 20 (36.36%) | 13 (43.33%) | 11 (28.2%) | 0 |
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Dyspnea with little effort | 20 (36.36%) | 5 (16.67%) | 16 (41.03%) | 0 |
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Dyspnea at rest | 15 (27.27% | 12 (40.00%) | 12 (30.77%) | 0 |
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P1 = 0.09, P2 = 0.37, P3 < 0.0001, P4 = 0.11, P5 < 0.0001, P6 < 0.0001 |