| Compound | Implementation Year | Recall Year | Damage Caused | Maximum Production | Regulation |
| Tetraethyl Lead | 1920 | 1990 | - Pollution - Toxicity | 7.2 × 109 L | Section 211 of the Clean Air Act |
| Asbestos | 1850’s | 2005 | - Cancer - Silicosis - Asbestosis | 5,000,000 ton | Basel Convention on the Control of Transboundary Movements of Hazardous Wastes and Their Disposal |
| Polymers | 1880’s | In use | Pollution | 348,000,000 ton/year | Unfinished |
| Cromates | 1890’s | In use | - Cancer - Pollution | 18,000,000 ton/year | Unfinished |
| Chlorofluoro carbonates | 1928 | 1995 | Degradation atmospheric ozone layer | 1,200,000 ton | Montreal Protocol on Substances that Deplete the Ozone Layer |