| Characteristic | Liposomal iron | Conventional Iron |
| Phospholipid Bilayer | Present | Absent |
| Effect of gastric acidity | None | Present |
| Oxidation of iron | No | Yes |
| Targeted iron delivery | Yes | No |
| Absorption of iron | Enhanced | Regular |
| Absorption via intestinal M cells | Yes | No |
| Food effect | No | Yes |
| Oxidative damage to intestinal epithelium | No | Yes |
| Gastrointestinal side effects | Minimal/Absent | Yes |
| Metallic taste | No | Yes |
| Chelation with other metals | No | Yes |