Parameters

Treatment

P-Value

T1

T2

T3

T4

Total protein, g/dl

5.40 ± 0.16

5.71 ± 0.28

5.83 ± 0.24

5.69 ± 0.19

0.5614

Albumin, g/dl

2.88 ± 0.07^c

3.06 ± 0.04^b

3.21 ± 0.05^a

3.01 ± 0.08^b

0.0001

Globulin, g/dl

2.52 ± 0.17

2.65 ± 0.25

2.62 ± 0.20

2.68 ± 0.22

0.9633

Total lipid, mg/dl

358.50 ± 9.15^a

330.33 ± 18.29^ab

313.00 ± 9.19^b

326.33 ± 9.64^b

0.0310

Cholesterol, mg/dl

153.17 ± 3.54^a

124.00 ± 5.85^b

129.67 ± 4.48^b

122.50 ± 2.68^b

0.0001

Triglyceride, mg/dl

72.33 ± 3.48

64.17 ± 3.40

67.67 ± 2.32

68.83 ± 2.61

0.3011

LDL, mg/dl

38.10 ± 2.09

36.25 ± 1.70

36.67 ± 2.20

35.50 ± 2.38

0.8596

HDL, mg/dl

41.67 ± 4.35^b

45.13 ± 3.14^ab

51.33 ± 6.48^ab

55.50 ± 5.30^a

0.0278

Glucose, mg/dl

233.00 ± 9.19^a

222.33 ± 19.03^a

212.33 ± 6.23^ab

198.00 ± 6.83^b

0.0389

Creatinine, mg/dl

0.77 ± 0.04

0.75 ± 0.03

0.71 ± 0.03

0.69 ± 0.03

0.3896

Uric acid, mg/dl

7.19 ± 0.67

6.97 ± 0.38

5.87 ± 0.23

6.37 ± 0.26

0.1405

AST, U/L

50.40 ± 1.84^a

45.43 ± 0.47^b

46.23 ± 0.99^b

47.57 ± 1.06^ab

0.0253

ALT, U/L

23.43 ± 0.73^a

19.85 ± 0.40^b

18.92 ± 0.55^b

20.35 ± 0.51^b

0.0007

ALP, IU/L

315.83 ± 15.09

313.22 ± 13.53

322.73 ± 12.06

323.81 ± 4.36

0.9179

Ca, mg/dl

10.93 ± 0.23^b

11.15 ± 0.13^ab

11.48 ± 0.07^a

11.11 ± 0.07^ab

0.0470

IP, mg/dl

5.65 ± 0.12^b

5.92 ± 0.13^ab

5.84 ± 0.19^ab

6.06 ± 0.04^a

0.0479

T₃, ng/ml

2.52 ± 0.06^b

2.69 ± 0.06^b

3.01 ± 0.23^a

3.06 ± 0.11^a

0.0001

IgG, mg/dl

34.32 ± 1.49^c

45.54 ± 2.29^b

53.32 ± 2.37^a

50.48 ± 2.07^a

0.0001

TAC, mM/L

1.11 ± 0.07^b

1.23 ± 0.10^ab

1.35 ± 0.02^a

1.42 ± 0.05^a

0.0409

MDA, IU/L

137.58 ± 5.12^a

135.09 ± 3.23^ab

124.02 ± 3.63^b

123.83 ± 2.94^b

0.0512