| Clinical signs | Effective | Frequency |
| Goiter | 38 | 95% |
| Exophthalmos | 26 | 65% |
| Cardinal syndrome | 22 | 55% |
| Weight loss | 16 | 40% |
| Pale mucous membranes | 10 | 25% |
| Asthenia | 10 | 25% |
| Hypometabolism syndrome | 9 | 22.5% |
| Melanoderma | 6 | 15% |
| Nausea, vomiting, diarrhea | 6 | 15% |
| Palpitations | 5 | 12.5% |
| Fever | 5 | 12.5% |
| Alopecia | 4 | 10% |
| Myxedematous syndrome | 4 | 10% |
| Neuropsychiatric disorders | 4 | 10% |
| Dyspnea | 3 | 7.5% |
| Erythema | 1 | 2.5% |
| Low blood pressure | 1 | 2.5% |
| High blood pressure | 1 | 2.5% |
| Polyarthralgias | 1 | 2.5% |