| Studies parameters | Goiter Grade 0 - 1 | Goiter Grade 2 | Goiter Grade 3 | p value | |
| Gender | Men (n = 244) | 49 (20.1%) | 87 (35.6%) | 108 (42.3%) | 0.000 |
| Female (n = 796) | 165 (20.7%) | 453 (56.9%) | 178 (22.4%) | ||
| Age | [0 - 25 years] (n = 404) | 45 (11.1%) | 209 (51.7%) | 150 (37.1%) | 0.000 |
| [26 - 50 years] (n = 535) | 131 (24.5%) | 282 (52.7%) | 122 (22.8%) | ||
| Over 50 years (n = 101) | 38 (37.6%) | 49 (48.5%) | 14 (13.9%) | ||
| Orbitopathy | Yes (n = 735) | 137 (18.6%) | 383 (52.1%) | 215 (29.3%) | 0.000 |
| No (n = 305) | 77 (25.2%) | 157 (51.5%) | 71 (23.3%) | ||