Group

First visit

After 2 weeks

After 4 weeks

After 6 weeks

ANOVA

F/p-value

Group A

Mean ± SD

13.74 ± 2.88

10.56 ± 2.518

7.37 ± 2.518

4.47 ± 2.72

F = 88.9

P*

-

<0.0001

<0.0001

<0.0001

Group B

Mean ± SD

12.84 ± 2.21

10.2 ± 1.75

6.84 ± 2.35

4.47 ± 2.72

F = 128.04

P*

-

<0.0001

<0.0001

<0.0001

p 0.0000