Antibiotic lock prophylaxis

No recommendation for routine prophylactic use [44] [45]

Preventive use is advocated to reduce the risk of CRBSI, but with caution to balance the benefits against the associated risk, and should not replace hygienic standards with regard to catheter care and handling [41]

Prophylactic use of antimicrobial catheter locking solution as a “plus measure”-unresolved issue [32]

“Use prophylactic antimicrobial lock solution in patients with long term catheters who have a history of multiple CRBSI despite optimal maximal adherence to aseptic technique” [17]