Mutation

Prob. deleterious

Loss of sheet

Gain of helix

Loss of loop

Glycos. S283

Gain of MoRF binding

A288S

0.253

(P = 0.0228)

(P = 0.0893)

(P = 0.2897)

(P = 0.4302)

(P = 0.4656)

M731T

0.937

(P = 0.1358)

(P = 0.1466)

(P = 0.1872)

(P = 0.2205)

(P = 0.2897)

R50Q

0.581

(P = 0.0115)

(P = 0.0921)

(P = 0.132)

(P = 0.1688)

(P = 0.1894)

K197N

0.075

(P = 0.02)

(P = 0.0668)

(P = 0.0997)

(P = 0.1299)

(P = 0.1579)

G460W

0.078

(P = 0.0549)

(P = 0.1312)

(P = 0.1551)

(P = 0.1736)

(P = 0.1907)

M731T

0.937

(P = 0.1358)

(P = 0.1466)

(P = 0.1872)

(P = 0.2205)

(P = 0.2897)

G75V

0.388

(P = 0.0359)

(P = 0.0477)

(P = 0.0556)

(P = 0.0609)

(P = 0.1131)