| Compounds | Target | Effect |
| Verteporfin | YAP | Inhibit YAP-TEAD interaction and transcriptional activity in vitro |
| Dobutamine | Β-adrenergic receptor agonist | Causes the suppression and accumulation of TEAD-YAP transcriptional activity in vitro |
| Botulinum toxin C3 | RHO | Inhibit YAP nuclear localization and TEAD activity |