| Recommended protocol | |||
| Spigelman stage | Endoscopic frequency | Chemoprevention | Surgery |
| Stage 0 | 5 years | (−) | (−) |
| Stage I | 5 years | (−) | (−) |
| Stage II | 3 years | (−) | (−) |
| Stage III | 12 months | (±) | (−) |
| Stage IV | 12 months | (+) | (+) |