Factor | Median PFS (95% CI) | p-value |
Performance status ECOG: |
|
|
0 | 7 (5.46 - 8.53) | 0.001* |
1 | 4 (3.31 - 4.68) | |
2 | 2 (1.23 - 2.74) | |
Αlpha-Fetoprotein decrement: |
|
|
Yes | 7 (6.24 - 7.75) | 0.001* |
No | 4 (2.88 - 5.11) | |
BCLC staging system: |
|
|
B | 7 (5.94 - 8.05) | 0.001* |
C | 3 (2.85 - 4.02) | |
Liver function by Child-Pugh stage: |
|
|
A | 6 (3.49 - 8.50) | 0.001* |
B | 4 (3.35 - 4.65) | |
C | 2 (2.00 - 2.00) | |
Response: |
|
|
PR | 7 (5.79 - 8.21) | 0.001* |
SD | 4 (3.51 - 4.48) | |
PD | 2 (2.00 - 2.00) |