| Primary tumor | Pre-surgery ctDNA | Post-surgery ctDNA | |||||||||||||||
| Case No. | Age | Histological type* | TNM** | Stage | ER | PgR | HER2*** | Ki-67 | Molecular subtype | PIK3CA | Fractional abundance | PIK3CA | Fractional abundance | PIK3CA | Fractional abundance | ||
| 1 | 55 | IDC | T2N0 | IIA | positive | negative | positive | 25% | luminal B | E542K | 1.6% | wild-type | wild-type | ||||
| 2 | 76 | ILC | T3N1 | IIIA | positive | negative | negative | <10% | luminal B | E545K | 11.0% | wild-type | wild-type | ||||
| 3 | 51 | IDC | T2N0 | IIA | positive | positive | negative | 12% | luminal A | E545K | 22.6% | wild-type | wild-type | ||||
| 4 | 79 | IDC | T2N0 | IIA | positive | negative | negative | 35% | luminal B | E545K | 16.2% | wild-type | wild-type | ||||
| 5 | 78 | IDC | T2N1 | IIB | positive | negative | negative | 6% | luminal B | E545K | 13.1% | E545K | 0.20% | wild-type | |||
| 6 | 75 | IDC | T1cN0 | IA | positive | positive | positive | >50% | luminal B | H1047R | 43.6% | H1047R | 0.54% | wild-type | |||
| 7 | 47 | ILC | T3N1 | IIIA | positive | positive | negative | 15% | luminal A | H1047R | 31.0% | H1047R | 0.96% | H1047R | 0.30% | ||
| 8 | 65 | IDC | T1bN0 | IA | negative | negative | positive | 9% | HER2 | H1047R | 10.2% | H1047R | 1.08% | H1047R | 0.27% | ||
| 9 | 85 | IDC | T1cN0 | IA | positive | positive | negative | 22% | luminal B | H1047R | 32.5% | wild-type | wild-type | ||||
| 10 | 79 | IDC | T2N1 | IIB | positive | positive | negative | 50% | luminal B | H1047R | 2.2% | wild-type | wild-type | ||||
| 11 | 75 | IDC | T2N0 | IIA | positive | positive | positive | 50% | luminal B | H1047R | 26.9% | wild-type | wild-type | ||||
| 12 | 84 | IDC | T1cN0 | IA | positive | positive | negative | 6% | luminal A | E542K | 3.8% | wild-type | wild-type | ||||
| H1047R | 22.5% | wild-type | wild-type | ||||||||||||||
| 13 | 39 | IDC | T1cN0 | IA | positive | positive | negative | 12% | luminal A | H1047R | 5.3% | wild-type | not collected | ||||
| 14 | 79 | IDC | T1cN0 | IA | positive | positive | negative | 16% | luminal A | wild-type | |||||||
| 15 | 56 | IDC | T1cN1 | IIA | positive | positive | negative | 22% | luminal B | wild-type | |||||||
| 16 | 81 | IDC | T2N0 | IIA | negative | negative | positive | >50% | HER2 | wild-type | |||||||
| 17 | 76 | IDC | T1cN0 | IA | positive | positive | negative | 11% | luminal A | wild-type | |||||||
| 18 | 31 | IDC | T2N0 | IIA | positive | positive | negative | 12% | luminal A | wild-type | |||||||
| 19 | 77 | IDC | T1cN0 | IA | positive | positive | negative | <10% | luminal A | wild-type | |||||||
| 20 | 47 | IDC | T1aN0 | IA | positive | positive | negative | 10% | luminal A | wild-type | |||||||
| 21 | 63 | IDC | T2N1 | IIB | positive | negative | negative | 13% | luminal B | wild-type | |||||||
| 22 | 51 | IDC | T2N0 | IIA | positive | positive | negative | 25% | luminal B | wild-type | |||||||
| 23 | 80 | IDC | T2N1 | IIB | positive | positive | negative | 25% | luminal B | wild-type | |||||||
| 24 | 83 | special type | T2N0 | IIA | positive | negative | negative | 12% | luminal B | wild-type | |||||||
| 25 | 59 | IDC | T1cN1 | IIA | positive | negative | negative | 8% | luminal B | wild-type | |||||||
| 26 | 44 | IDC | T2N0 | IIA | positive | positive | negative | 22% | luminal B | wild-type | |||||||
| 27 | 75 | IDC | T2N0 | IIA | positive | positive | negative | 22% | luminal B | wild-type | |||||||