|
| All grade | Grade ≥ 3 |
| Hypertension | 22 (84.6) | 19 (73.1) |
| Fatigue | 19 (73.1) | 1 (3.8) |
| Hand-foot syndrome | 16 (61.5) | 3 (11.5) |
| Hypothyroidism | 16 (61.5) | 0 |
| Dysphonia | 15 (57.7) | 0 |
| Diarrhea | 12 (46.2) | 0 |
| Decreased appetite | 8 (30.8) | 2 (7.7) |
| Stomatitis | 8 (30.8) | 0 |
| Rash | 6 (23.1) | 1 (3.8) |
| Dysgeusia | 5 (19.2) | 0 |
| Nausea | 4 (15.4) | 2 (7.7) |
| Vomiting | 4 (15.4) | 0 |
| Constipation | 4 (15.4) | 0 |
| Laboratory abnormalities |
|
|
| Proteinurea | 20 (76.9) | 5 (19.2) |
| Blood uric acid increased | 11 (42.3) | 0 |
| Blood creatinine increased | 8 (30.8) | 0 |
| ALT increased | 8 (30.8) | 0 |
| Thrombocytopenia | 8 (30.8) | 0 |
| Anemia | 5 (19.2) | 1 (3.8) |
| AST increased | 5 (19.2) | 0 |