| Confirmation of diagnosis | Treatment | Confirmation of recurrence | Confirmation of response to PBT | Molecular profiling | ||||||||
| Pathology | Radiology | |||||||||||
| Patient | Place and date | Diagnosis | Place and date | Diagnosis | Place and date | Assessment | Place and date | Assessment | OSD (days) | OST (days) | ||
| 1 | Regional medical center February 20, 2007 | APMD | Regional radiology CT February 1, 2007 | Large pancreatic mass (head and body) | Gemcitabine and oxaliplatin February-July 12, 2007 | Regional medical center CT June 19, 2007 | Recurrence |
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| Multiple liver, spleen, and lymph nodes metastases | 5-fluorouracil + leucovorin July 15-November 1, 2007 | Regional medical center CT November 6, 2007 | Recurrence |
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| Stage at admission to BC: IVB, recurrent | BC. November 28, 2007. PB, erlotinib, capecitabine, BVZ |
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| Regional radiology PET/CT February 19, 2008 | SD | 853 | 572 | VEGF- elevated (blood) |
| 2 | Cancer institute October 29, 2008 | APMD | Regional hospital CT September 5, 2008 | Mass in pancreatic head | Whipple procedure September 9, 2008 |
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| Infiltration of portal and superior mesenteric vein. Multiple liver, lung, and lymph node metastases. | Gemcitabine x3 November- December 2009 | Cancer institute CT February 22, 2009 | Recurrence |
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| Stage at admission to BC: IVB, recurrent | BC. March 12, 2009 PB, sorafenib, rapamycin, erlotinib, vorinostat, BVZ. Discontinued sorafenib, vorinostat, erlotinib, BVZ May 27, 2009 capecitabine, oxaliplatin |
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| Regional radiology PET/CT June 8, 2009 | PR | 486 | 302 | VEGF- elevated (blood) |
| 3 | Regional hospital May 13, 2008 | APMD | Regional radiology CT March 26, 2008 | Mass in body and tail of pancreas | Whipple procedure, splenectomy, wedge resections of the stomach May 9, 2008 |
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