Cohort

Week

Visit Date

IFN-γ(pg/mL)

IL-6(pg/mL)

TNF-alpha(pg/mL)

hsCRP(mg/L)

MPO(ng/mL)

MDA(ng/mL)

A

Ave (SD)

1

2016/11/14

5.91 (3.61)

0.30 (0.21)

1.36 (0.57)

0.81 (0.69)

20.11 (7.34)

9.54 (14.68)

Ave (SD)

5

2016/12/14

7.45 (3.12)

0.68 (0.65)

1.31 (0.42)

1.49 (2.74)

21.40 (7.22)

4.80 (1.44)

Ave (SD)

6

2016/12/22

10.39 (5.88)

0.48 (0.54)

1.42 (0.59)

2.26 (2.92)

21.68 (6.20)

8.40 (9.28)

W1 vs W5

0.156

0.118

0.389

0.227

0.156

0.074

W1 vs W6

0.035

0.107

0.273

0.096

0.191

0.191

W5 vs W6

0.040

0.219

0.230

0.109

0.363

0.180

B

Ave (SD)

1

2017/1/9

5.75 (2.11)

0.42 (0.28)

0.89 (0.15)

0.75 (0.68)

15.44 (6.70)

7.32 (4.14)

Ave (SD)

5

2017/2/9

7.10 (5.36)

0.55 (0.50)

1.11 (0.27)

0.61 (0.46)

16.46 (6.11)

9.67 (9.01)

Ave (SD)

6

2017/2/16

4.55 (1.65)

0.62 (0.54)

0.98 (0.13)

1.35 (0.70)

14.26 (4.42)

10.14 (8.92)

W1 vs W5

0.167

0.260

0.098

0.353

0.331

0.241

W1 vs W6

0.078

0.191

0.023

0.034

0.306

0.421

W5 vs W6

0.068

0.188

0.124

0.019

0.218

0.297

A + B

Ave (SD)

1

5.83 (2.86)

0.35 (0.24)

1.17 (0.48)

0.78 (0.66)

17.78 (7.21)

8.50 (10.79)

Ave (SD)

5

7.29 (4.15)

0.61 (0.55)

1.21 (0.36)

1.05 (1.94)

18.93 (6.95)

7.40 (6.27)

Ave (SD)

6

7.66 (5.25)

0.55 (0.52)

1.22 (0.48)

1.81 (2.09)

18.22 (6.50)

9.21 (8.83)

W1 vs W5

0.094

0.207

0.227

0.090

0.229

0.210

W1 vs W6

0.180

0.232

0.047

0.015

0.138

0.316

W5 vs W6

0.395

0.339

0.385

0.017

0.363

0.341