● Health is defined as maintaining low entropy

● Disease is a failure to maintain low entropy

● Entropy, introducing changes in DNA, favors evolution so life can survive in a changing environment

● Fetal development is an ordering of substrates and requires negative entropy with the energy supplied by the environment

● Repair of Injury depends on the developmental state. Prior to birth, injury is directed toward complete functional repair (negative entropy). After birth, repair is directed toward rapid return of partial function at the expense of achieving complete repair (positive entropy)

● Age is a state of increasing entropy

● Biologic processes are time dependent ordered by information provided by DNA. At the end of each process there are statistical possibilities for the next step. The energy required for this step is negative entropy = k * LOG (1/D).

● A strategy that saves energy by supplying a catalyst, carrier protein, or electromagnetic force assures the next critical step has the lowest energy.

● Drug discovery finds the catalyst, carrier protein, or electromagnetic force that favors negative entropy