LncRNA

Target gene

Major methods and subject

Role or function

Cataract classification

reference

KCNQ1OT1↑

SMAD4

TGF-β2 induced SRA01/02 in vitro

HLECs proliferation and EMT

ASC and PCO

[31]

KCNQ1OT1↑

MiR-214/caspase-1

induced SRA01/04 cell in vitro

Promote HLECs Pyroptosis,

ARC

[12]

FEZF1-AS1↑

FEZF1

induced SRA01/04 cell in vitro

Promote HLECs proliferation

PCO

[39]

MIAT↑

MiRNA-150-5p/Akt

SRA01/04 cell in vitro

Increase HLECs proliferation and viability; decrease HLECs dead or dying

PCO

[34]

H19↑

miRNA-675-5p

HECs in vitro

Increase HLECs proliferation and migration, decrease HLECs dead or dying

Nuclear cataract

[33]

H19↑

miR-29

HECs in vitro

Increase HLECs proliferation and migration, decrease HLECs apoptosis

ARC

[36]

TUG1↑

MiRNA-214

HECs in vitro

Promote HLECs apoptosis,

cataract

[37]

MALAT1↑

P38

HECs in vitro

Promote HLECs apoptosis

Diabetic cataract

[32]

PLCD3-OT1↓

MiR-224-5P

induced SRA01/04 cell in vitro

Inhibit HLECs apoptosis

ARC

[38]