miRNA | Expression | Target | Cataract type | Function | reference |
miR-26a/b | down | Jagged-1/Notch | ASC and PCO | suppress LEC proliferation, migration and EMT | [11] |
miR-30a | down | BECN-1 | DC | regulation of autophagy and apoptosis in LECs | [22] |
miR-30a | down | SNAI1 | DC | inhibit EMT | [23] |
miRNA-204-5p | down | TGFβ/SMAD4 | PCO | inhibit EMT | [24] |
miR-181a | down | c-Met, slug, COX-2 | PCO | suppress the migration, proliferation, and EMT of LECs | [18] |
miR-34a | up | Notch2 | ARC | promote LECs apoptosis | [25] |
miR-34a | up | Bcl-2, SIRT-1 | ARC | promote LECs apoptosis | [20] |