miRNA

Expression

Target

Cataract type

Function

reference

miR-26a/b

down

Jagged-1/Notch

ASC and PCO

suppress LEC proliferation,

migration and EMT

[11]

miR-30a

down

BECN-1

DC

regulation of autophagy and apoptosis in LECs

[22]

miR-30a

down

SNAI1

DC

inhibit EMT

[23]

miRNA-204-5p

down

TGFβ/SMAD4

PCO

inhibit EMT

[24]

miR-181a

down

c-Met, slug, COX-2

PCO

suppress the migration, proliferation, and EMT of LECs

[18]

miR-34a

up

Notch2

ARC

promote LECs apoptosis

[25]

miR-34a

up

Bcl-2, SIRT-1

ARC

promote LECs apoptosis

[20]