Estimated peptide

Comparative Analysis

Ratio

F4404 vs. SM

F4408 vs. SM

Ala-Ser Thr-Gly

3.5

3.4

Ala-Thr Thr-Ala

<1

<1

Arg-Glu Glu-Arg

<1

<1

Arg-Gly Gly-Arg

<1

<1

Arg-Pro

<1

<1

Asn-Asp Asp-Asn

1.1

1.8

Asn-Ile Asn-Leu Ile-Asn Leu-Asn Val-Gln

N.A.

1<

Asn-Thr Ser-Gln Thr-Asn

<1

<1

Asp-Arg

1.2

1.3

Asp-Asp

<1

4.2

Asp-Glu

<1

1.4

Asp-Gly

0.7

0.8

Asp-Lys

0.9

1.1

Asp-Ser Ser-Asp

<1

<1

Daminozide Ala-Ala

22

15

Glu-Asp

<1

1.1

Glu-Glu

<1

0.5

Glu-Ser

<1

0.7

Gly-Asp

<1

1.0

Gly-Gly

N.A.

1<

Gly-His

His-Gly

<1

<1

Gly-Lys Lys-Gly

<1

0.9

Ile-Ala Leu-Ala

N.A.

1<

Ile-Lys Lys-Ile Lys-Leu Leu-Lys

<1

0.5