Mutation

Prevalence

BRAF V600E

45%

RET/PTC

20%

Copy Gain PI3KCA

12%

RAS

10%

PTEN

<10%

PI3KCA

<10%

TRK rearrangements

Beta catenin

HMGA2 overexpression

Insulin like growth factor II mRNA-binding protein 3 (IMP3)