Variable | Total, n | Node negative n (%) | Node positive n (%) | p |
Age at diagnosis ≤64 years >64 years |
73 67 |
43 (58.9) 45 (67.2) |
30 (41.1) 22 (32.8) | 0.40 |
Sex Male Female |
112 28 |
73 (34.8) 15 (46.4) |
39 (65.2) 13 (53.6) | 0.36 |
Tumor site Oral cavity Pharynx Larynx |
57 27 56 |
40 (70.2) 3 (11.1) 45 (80.4) |
17 (29.8) 24 (88.9) 11 (19.6) | <<0.0001 |
Differentiation Well Moderate and poor |
89 51 |
64 (71.9) 24 (47.1) |
25 (28.1) 27 (52.9) | 0.014 |
T stage T1, 2 T3, 4 |
62 78 |
46 (74.2) 42 (53.8) |
16 (25.8) 36 (46.2) | 0.021 |
VEGF-A High > 2.74 Low ≤ 2.74 |
55 85 |
25 (45.5) 63 (74.1) |
30 (54.5) 22 (25.9) | 0.001 |
Ki-67 High > 58.61% Low ≤ 58.61% |
55 85 |
31 (56.4) 58 (68.2) |
24 (43.6) 27 (31.8) | 0.21 |
Combined expression Both high Either high Neither high |
27 59 54 |
11 (40.7) 36 (61) 41 (75.9) |
16 (59.3) 23 (39) 13 (24.1) | 0.008 |