Aspect

Methylation array

Spatial transcriptomics

Field

Epigenetics

Genetic expression

Technique

Optimized for FFPE and Frozen tissue

Optimized for FFPE and Frozen tissue

Diagnostic or ancillary technique

Yes

Not yet

Revealing molecular heterogeneity of tissues in health and disease

Yes

Yes

Under development and verification for absolute diagnostic and clinical applications

Yes

Yes

Discovery of different and novel genetic or epigenetic alterations

Yes

Yes

Classification of tumors

Yes

Under development

Elucidate diagnostic and prognostic markers

Yes

Yes

Detection of therapeutic checkpoints.

Yes

Yes

Detect the resistance of response for certain type of treatment

Yes

Yes

Applications in neuropathology

Research and support diagnostic tool

Research tool