Aspect | Methylation array | Spatial transcriptomics |
Field | Epigenetics | Genetic expression |
Technique | Optimized for FFPE and Frozen tissue | Optimized for FFPE and Frozen tissue |
Diagnostic or ancillary technique | Yes | Not yet |
Revealing molecular heterogeneity of tissues in health and disease | Yes | Yes |
Under development and verification for absolute diagnostic and clinical applications | Yes | Yes |
Discovery of different and novel genetic or epigenetic alterations | Yes | Yes |
Classification of tumors | Yes | Under development |
Elucidate diagnostic and prognostic markers | Yes | Yes |
Detection of therapeutic checkpoints. | Yes | Yes |
Detect the resistance of response for certain type of treatment | Yes | Yes |
Applications in neuropathology | Research and support diagnostic tool | Research tool |