Stage C

18 (30%)

6 (33.3%)

12 (66.7%)

6 (33.3%)

12 (66.7%)

10 (55.6%)

8 (44.4%)

Stage D

17 (28.3%)

2 (11.8%)

15 (88.2%)

5 (29.4%)

12 (70.6%)

14 (82.4%)

3 (17.6%)

AJCC stage

Stage I

14 (23.3%)

14 (100%)

0 (0%)

<0.001§

14 (100%)

0 (0%)

<0.001§

2 (14.3%)

12 (85.7%)

<0.001§

Stage II

12 (20%)

8 (66.7%)

4 (33.3%)

7 (58.3%)

5 (41.7%)

3 (25%)

9 (75%)

Stage III

17 (28.3%)

5 (29.4%)

12 (70.6%)

5 (29.4%)

12 (70.6%)

10 (58.8%)

7 (41.2%)

Stage IV

17 (28.3%)

2 (11.8%)

15 (88.2%)

5 (29.4%)

12 (70.6%)

14 (82.4%)

3 (17.6%)

COX2

Low

29 (48.3%)

22 (75.9%)

7 (24.1%)

<0.001

8 (27.6%)

21 (72.4%)

0.002

High

31 (51.7%)

9 (29%)

22 (71%)

21 (67.7%)

10 (32.3%)

Cyclin D1

Low

31 (51.7%)

22 (71%)

9 (29%)

<0.001

9 (29%)

22 (71%)

0.002

High

29 (48.3%)

7 (24.1%)

22 (75.9%)

20 (69%)

9 (31%)

P21

Low

29 (48.3%)

8 (27.6%)

21 (72.4%)

0.002

9 (31%)

20 (69%)

0.002

High

31 (51.7%)

21 (67.7%)

10 (32.3%)

22 (71%)

9 (29%)