| Efficacy/Safety |
| warfarin | NOAC |
| Hernandez, et al., 2018 | favors |
| ü |
| Kanai, et al., 2018 | favors |
| ü |
| Cost |
| warfarin | NOAC |
| Harrington, et al., 2013 | favors |
| ü |
| Reddy, et al., 2015 | favors |
| ü |
| Lee, et al., 2012 | favors |
| ü |
| Merli, et al., 2016 | favors |
| ü |
| Xie, et al., 2016 | favors |
| ü |
| Real-World Evidence |
| warfarin | NOAC |
| Beyer-Westendorf, 2018 | favors |
| ü |
| Lip, et al., 2016 | favors |
| ü |
| Patient Satisfaction |
| warfarin | NOAC |
| Vrijens & Heidbuchel, 2015 | favors |
| ü |
| Clarkesmith, et al., 2017 | favors |
| ü |