| Current | MIDUS | |
| (N = 132)1 | (N = 570)2 | |
| Demographics | % (N) Mean (SD) | % (N) Mean (SD) |
| Age, years | 51.6 (13.5) | 59.2 (11.7) |
| Education, years | 15.1 (3.3) | 14.8 (2.7) |
| Gender (% women) | 68.9 (91) | 53.7 (307) |
| Race (% white) | 53.0 (70) | 92.0 (526) |
| Depression | ||
| Beck Depression Inventory | 25.3 (8.5) | --- |
| CES-D | 9.0 (10.3) | |
| Pro-inflammatory cytokines | Median (range) | Median (range) |
| CRP (ng/ml)3 | 4.4 (0.2 - 38.1) | 1.3 (0.1 - 61.7) |
| TNF-α (pg/ml) | 6.3 (2.4 - 33.2) | --- |
| IL-1β (pg/ml) | 1.1 (0.01 - 10.3) | --- |
| IFN-γ (pg/ml) | 7.3 (0.03 - 49.7) | --- |
| IL-6 (pg/ml) | 2.1 (0.01 - 12.7) | 2.1 (0.2 - 23.0) |
| IL-12(p70) (pg/ml) | 2.5 (0.01 - 25.4) | --- |
| Anti-inflammatory cytokines | ||
| IL-1RA (pg/ml) | 10.1 (0.2 - 454.2) | --- |
| IL-4 (pg/ml) | 9.7 (0.01 - 98.5) | --- |
| IL-10 (pg/ml) | 6.2 (0.02 - 86.5) | --- |
| Cytokine ratios (pro-/anti-inflammatory) | ||
| TNF-α/IL-4 | 0.6 (0.08 - 818.0) | --- |
| TNF-α/IL-10 | 1.1 (0.07 - 260.0) | --- |
| IL-1β/IL-1RA | 0.1 (0.0 - 30.1) | --- |
| IL-1β/IL-10 | 0.2 (0.0 - 16.0) | --- |
| IL-1β/IL-4 | 0.1 (0.0 - 52.9) | --- |
| IL-6/IL-10 | 0.3 (0.0 - 92.0) | --- |
| IL-6/IL-4 | 0.2 (0.0 - 40.0) | --- |
| IFN-γ/IL-4 | 0.8 (0.01 - 450.0) | --- |
| IFN-γ/IL-10 | 1.3 (0.01 - 245.0) | --- |
| IL-12/IL-10 | 0.4 (0.0 - 46.0) | --- |
| IL-12/IL-4 | 0.2 (0.0 - 74.0) | --- |
| Stress hormones | ||
| CORT (mg/L creatinine) | 30.2 (1.3 - 136.0) | 11.0 (0.4 - 212.0) |
| EPI (mg/L creatinine) | 5.4 (0.0 - 131.4) | 1.8 (0.3 - 10.6) |
| NE (mg/L creatinine) | 39.5 (3.6 - 320.1) | 26.0 (3.5 - 187.1) |