Subject

Group

Baseline

Follow-Up Week

1st Month

3rd Month

6th Month

1

Placebo

296

175

187

192

2

Placebo

376

329

236

76

3

Placebo

150

?(150*)

?(150*)

?(150*)

4

Active

282

186

225

134

5

Active

317

31

85

120

6

Active

362

104

?(104*)

?(104*)