Step 1

Peer-reviewed distinguished scientific literature Science, Nature, J. Cancer Therapy, Am Soc Nutrition Journals

Select nutrients that are described as reducing age-associated diseases

Step 2

Review secondary sources in peer-reviewed journals

Look for evidence in vitro and in vivo studies demonstrating effectiveness

Step 3

Review ingredients to ensure safety and that synergistic effects are beneficial

Step 4

Determine whether combined ingredients are already available in common supplements like AREDs

Step 5

Determine useful human dosage and frequency based on capsule size