Univariate analysis adjusted by risk factor | ||||
Risk Factor | Patients with aGVHD and risk factor | OR | 95% CI | p-value |
Peripheral blood | 23 | 6.25 | 2.39 - 16.28 | 0.001 |
Bone marrow | 1 | 0.9 | 0.90 - 9.04 | 0.7 |
umbilical cord | 3 | 0.15 | 0.45 - 0.53 | 0.001 |
Total body irradiation | 10 | 1.96 | 0.76 - 5.03 | 0.12 |
Infection 3 months prior to allogeneic transplant | 8 | 2.4 | 0.84 - 6.78 | 0.84 |
HLA-matched unrelated | 1 | 1.1 | 0.20 - 6.06 | 0.64 |
HLA-non-matched unrelated | 4 | 1.66 | 0.44 - 6.19 | 0.32 |
Donor/recipient Female/male | 9 | 2.58 | 0.94 - 7.10 | 0.05 |
Bacteremia within the first 7 days post-transplant, n | 12 | 1.38 | 0.57 - 3.35 | 0.3 |
CMV infection in the recipient | 4 | 4.11 | 0.85 - 19.68 | 0.03 |
PB > BM | 20 | 12.3 | 4.46 - 33.92 | 0.001 |
Cell dose > 8.3 × 106/kg | 3 | 7.1 | 1.09 - 46.24 | 0.05 |