Characteristics | All (N = 45) | BCL-2 | p-value | ||||
<10% (N = 8) | >10% (N = 37) | ||||||
No. | (%) | No. | (%) | No. | (%) | ||
Age (years) |
|
|
|
|
|
|
|
Mean ± SD | 56.31 | ± 12.3 | 52.62 | ± 12.83 | 57.10 | ± 12.12 | 0.298• |
Median (Range) | 54 | (38 - 74) | 45.50 | (42 - 73) | 54 | (38 - 74) | |
≤60 years | 25 | (55.6%) | 5 | (20%) | 20 | (80%) | 0.716 |
>60 years | 20 | (44.4%) | 3 | (15%) | 17 | (85%) | |
Sex |
|
|
|
|
|
|
|
Male | 26 | (57.8%) | 6 | (23.1%) | 20 | (76.9%) | 0.435 |
Female | 19 | (42.2%) | 2 | (10.5%) | 17 | (89.5%) | |
Rai classification |
|
|
|
|
|
|
|
Stage 0, 1 & 2 | 20 | (44.4%) | 7 | (35%) | 13 | (65%) | 0.015 |
Stage 3 & 4 | 25 | (55.6%) | 1 | (4%) | 24 | (96%) | |
Hepatomegally |
|
|
|
|
|
|
|
Absent | 23 | (51.1%) | 6 | (26.1%) | 17 | (73.9%) | 0.243 |
Present | 22 | (48.9%) | 2 | (9.1%) | 20 | (90.9%) | |
Lymphadenopathy |
|
|
|
|
|
|
|
Absent | 14 | (31.1%) | 3 | (21.4%) | 11 | (78.6%) | 0.689 |
Present | 31 | (68.9%) | 5 | (16.1%) | 26 | (83.9%) | |
Spleenomegally |
|
|
|
|
|
|
|
Absent | 12 | (26.7%) | 5 | (41.7%) | 7 | (58.3%) | 0.022 |
Present | 33 | (73.3%) | 3 | (9.1%) | 30 | (90.9%) | |
WBCs (×103/mm3) |
|
|
|
|
|
|
|
Mean ± SD | 46.80 | ±31.71 | 25.85 | ±8.49 | 51.33 | ±33.11 | 0.014• |
Median (Range) | 31.60 | (17.50 - 122.80) | 25 | (17.50 - 38) | 36 | (17.50 - 122.80) | |
<100 × 103/mm3 | 39 | (86.7%) | 8 | (20.5%) | 31 | (79.5%) | 0.572 |
≥100 × 103/mm3 | 6 | (13.3%) | 0 | (0%) | 6 | (100%) | |
Absolute lymphocytes (×103/mm3) |
|
|
|
|
|
|
|
Mean ± SD | 26.27 | ±16.42 | 17.01 | ±6.67 | 28.28 | ±17.25 | 0.085• |
Median (Range) | 18 | (9.10 - 67) | 17 | (9.10 - 26) | 19 | (12.50 - 67) | |
<30 × 103/mm3 | 33 | (73.3%) | 8 | (20.5%) | 25 | (75.8%) | 0.087§ |
≥30 × 103/mm3 | 12 | (26.7%) | 0 | (0%) | 12 | (100%) | |
Platelet count (×103/mm3) |
|
|
|
|
|
|
|
Mean ± SD | 121.13 | ±47.20 | 125 | ±46.94 | 120.29 | ±47.86 | 0.778• |
Median (Range) | 111 | (45 - 205) | 111 | (76 - 200) | 112 | (45 - 205) | |
<100 × 103/mm3 | 19 | (42.2%) | 2 | (10.5%) | 17 | (89.5%) | 0.435§ |
≥100 × 103/mm3 | 26 | (57.8%) | 6 | (23.1%) | 20 | (76.9%) | |
Hemoglobin (g/dl) |
|
|
|
|
|
|
|
Mean ± SD | 10.73 | ±2.29 | 11.73 | ±2.73 | 10.51 | ±2.17 | 0.191• |
Median (Range) | 10.20 | (6.60 - 14.30) | 12.65 | (7 - 14.30) | 10.10 | (6.60 - 14) | |
<12 g/dl | 25 | (55.6%) | 2 | (8%) | 23 | (92%) | 0.113 |
≥12 g/dl | 20 | (44.4%) | 6 | (30%) | 14 | (70%) |