Coomb’s test

Negative

38

(84.4%)

16

(42.1%)

22

(57.9%)

0.684

Positive

7

(15.6%)

2

(28.6%)

5

(71.4%)

Lymphocytic doubling time

<12 months

21

(46.7%)

12

(57.1%)

9

(42.9%)

0.028

>12 months

24

(53.3%)

6

(25%)

18

(75%)

Cytogenetic analysis

Normal

20

(44.4%)

8

(40%)

12

(60%)

0.20

del 13

4

(8.9%)

3

(75%)

1

(25%)

del 11

5

(11.1%)

3

(60%)

2

(40%)

Trisomy 12

6

(13.3%)

3

(50%)

3

(50%)

del 17

5

(11.1%)

0

(0%)

5

(100%)

Complex

5

(11.1%)

1

(20%)

4

(80%)

CD38 (%)

Mean ± SD

23.79

±25.41

19.07

±23.48

26.94

±26.58

0.431•

Median (Range)

8

(0.30 - 91.59)

5.93

(0.30 - 91.57)

32

(0.60 - 91.59)

<30%

28

(62.2%)

16

(57.1%)

12

(42.9%)

0.003

>30%

17

(37.8%)

2

(11.8%)

15

(88.2%)

BCL-2 (%)

Mean ± SD

52.20

±29.24

51.59

±30.40

52.61

±29.03

0.981•

Median (Range)

53.90

(2 - 93.20)

53.90

(3 - 93.20)

48.20

(2 - 91.20)

<10%

8

(17.8%)

4

(50%)

4

(50%)

0.694§

>10%

37

(82.2%)

14

(37.8%)

23

(62.2%)

ZAP-70

<20%

27

(60%)

9

(33.3%)

18

(66.7%)

0.264

>20%

18

(40%)

9

(50%)

9

(50%)

BCL-2/Bax ratio

Mean ± SD

2.01

±1.50

1.53

±1.30

2.32

±1.56

0.085•

Median (Range)

1.20

(0.30 - 5)

1

(0.30 - 4.30)

2

(0.50 - 5)

≤1.6

26

(57.8%)

13

(50%)

13

(50%)

0.109

>1.6

19

(42.2%)

5

(26.3%)

14

(73.7%)