<100 × 103/mm3 | 17 | (43.6%) | 13 | (76.5%) | 4 | (23.5%) | 0.002§ |
≥100 × 103/mm3 | 22 | (56.4%) | 6 | (27.3%) | 16 | (72.7%) | |
Hemoglobin (g/dl) |
|
|
|
|
|
|
|
Mean ± SD | 10.79 | ±2.25 | 9.59 | ±2.01 | 11.93 | ±1.87 | 0.002• |
Median (Range) | 10.20 | (6.60 - 14.30) | 9.10 | (6.60 - 14) | 12.95 | (7.70 - 14.30) | |
<11 g/dl | 22 | (56.4%) | 16 | (72.7%) | 6 | (27.3%) | 0.001§ |
≥11 g/dl | 17 | (43.6%) | 3 | (17.6%) | 14 | (82.4%) | |
LDH (U/L) |
|
|
|
|
|
|
|
Mean ± SD | 363.84 | ±108.13 | 419.47 | ±96.29 | 311 | ±96.56 | 0.002• |
Median (Range) | 380 | (190 - 540) | 430 | (210 - 540) | 300 | (190 - 500) | |
≤350 U/L | 18 | (46.2%) | 4 | (22.2%) | 14 | (77.8%) | 0.002§ |
>350 U/L | 21 | (53.8%) | 15 | (71.4%) | 6 | (28.6%) | |
B2-microglobulin (mg/L) |
|
|
|
|
|
|
|
Mean ± SD | 3.01 | ±0.97 | 3.25 | ±0.95 | 2.78 | ±0.96 | 0.130• |
Median (Range) | 3 | (1.80 - 5) | 3.30 | (2 - 5) | 2.05 | (1.80 - 4.40) | |
<3.5 mg/L | 24 | (61.5%) | 11 | (45.8%) | 13 | (54.2%) | 0.648§ |
≥3.5 mg/L | 15 | (38.5%) | 8 | (53.3%) | 7 | (46.7%) | |
Coomb’s test |
|
|
|
|
|
|
|
Negative | 32 | (82.1%) | 13 | (40.6%) | 19 | (59.4%) | 0.044• |
Positive | 7 | (17.9%) | 6 | (85.7%) | 1 | (14.3%) | |
Lymphocytic doubling time |
|
|
|
|
|
|
|
<12 months | 18 | (46.2%) | 3 | (16.7%) | 15 | (83.3%) | <0.001§ |
>12 months | 21 | (53.8%) | 16 | (76.2%) | 5 | (23.8%) | |
Cytogenetic analysis |
|
|
|
|
|
|
|
Normal | 17 | (43.6%) | 5 | (29.4%) | 12 | (70.6%) | 0.002§ |
del 13 | 3 | (7.7%) | 1 | (33.3%) | 2 | (66.7%) | |
del 11 | 4 | (10.3%) | 3 | (75%) | 1 | (25%) | |
Trisomy 12 | 5 | (12.8%) | 0 | (0%) | 5 | (100%) | |
del 17 | 5 | (12.8%) | 5 | (100%) | 0 | (0%) | |
Complex | 5 | (12.8%) | 5 | (100%) | 0 | (0%) | |
CD38 (%) |
|
|
|
|
|
|
|
Mean ± SD | 25.94 | ±26.21 | 41.69 | ±27.74 | 10.98 | ±12.70 | <0.001• |
Median (Range) | 22 | (0.30 - 91.59) | 38 | (0.72 - 91.59) | 4.59 | (0.30 - 42) | |
<30% | 23 | (59%) | 4 | (17.4%) | 19 | (82.6%) | <0.001§ |
>30% | 16 | (41%) | 15 | (93.8%) | 1 | (6.3%) | |
ZAP-70 |
|
|
|
|
|
|
|
<20% | 24 | (61.5%) | 16 | (66.7%) | 8 | (33.3%) | 0.005§ |
>20% | 15 | (38.5%) | 3 | (20%) | 12 | (80%) |