Variable

Frequency

Median (age yrs)

52

Sex

Male

Female

17

13

Hypertensive before study

Normotensive before study

7

23

No of metastatic sites

1

>1

21

9

Performance status

0

1

2

3

14

12

3

1

FOLFOX chemotherapy

CapeOX chemotherapy

21

9

Median no of cycles of Bevacizumab

9

Antihypertensive treatment before start of bevacizumab (n = 7)

Calcium channel blockers

Angiotensin Converting enzyme inhibitor

Beta blockers

Combination

3

1

1

2

Family history of hypertension

Yes

No

5

25

Primary tumour

Colon

Recto sigmoid

Rectum

20

2

8

Metastatic site

Liver alone

Lung alone

Bone alone

Multiple

17

2

2

9

CEA (ng/ml)

<10

>10

3

27