Clinicopathological characteristics | Overall survival (n = 1402) | Rrgerreion-free survival (n = 3951) | |||||
N | Hazard ration | P-value | N | Hazard ration | P-value | ||
ER | positive | 2565 | 1.61 (1.24 - 2.09) | ** | 2565 | 1.61 (1.37 - 1.90) | *** |
negative | 1214 | 1.10 (0.75 - 1.63) | 0.6200 | 1214 | 1.16 (0.93 - 1.46) | 0.1900 | |
PR | postive | 954 | 1.34 (0.35 - 5.09) | 0.6700 | 954 | 1.36 (0.96 - 1.93) | 0.0811 |
negative | 1028 | 1.01 (0.40 - 2.55) | 0.9800 | 1028 | 1.06 (0.79 - 1.42) | 0.6969 | |
HER2 | postive | 416 | 1.25 (0.62 - 2.50) | 0.5300 | 416 | 0.94 (0.61 - 1.45) | 0.7917 |
negative | 1456 | 2.43 (0.94 - 6.28) | 0.0580 | 1456 | 1.86 (1.42 - 2.44) | *** | |
Intrinsic subtype | basal | 879 | 1.65 (1.00 - 2.71) | 0.0480 | 879 | 1.20 (0.94 - 1.55) | 0.1483 |
luminal A | 2504 | 1.72 (1.20 - 2.47) | 0.0028 | 2504 | 1.89 (1.58 - 2.25) | *** | |
luminal B | 1425 | 1.30 (0.90 - 1.89) | 0.1600 | 1425 | 1.28 (1.06 - 1.55) | 0.0113 | |
HER2+ | 335 | 0.57 (0.29 - 1.11) | 0.0940 | 335 | 0.76 (0.52 - 1.12) | 0.1593 | |
lymph node status | postive | 1459 | 1.13 (0.76 - 1.66) | 0.5500 | 1459 | 1.67 (1.37 - 2.03) | *** |
negative | 2259 | 2.00 (1.36 - 2.92) | ** | 2259 | 1.63 (1.37 - 1.93) | *** | |
Grade | 1 | 378 | 1.94 (0.76 - 4.94) | 0.1600 | 378 | 1.50 (0.89 - 2.52) | 0.1242 |
2 | 1077 | 1.75 (1.13 - 2.70) | 0.0110 | 1077 | 1.60 (1.26 - 2.05) | ** | |
3 | 1099 | 1.10 (0.80 - 1.53) | 0.5600 | 1090 | 1.13 (0.91 - 1.40) | 0.2809 | |
TP53 status | mutated | 232 | 0.53(0.24 - 1.19) | 0.1200 | 232 | 0.84 (0.59 - 1.51) | 0.7969 |
wild type | 363 | 1.77 (0.91 - 3.45) | 0.0870 | 363 | 1.40 (0.91 - 2.13) | 0.1204 |