Quartiles of resting heart rate

Whole cohort

(n = 832)

I quartile

(n = 208)

II quartile

(n = 208)

III quartile

(n = 208)

IV quartile

(n = 208)

p-value

for trend

Continuous variables

Resting heart rate (bpm)

67.1 ± 10.6

55.1 ± 4.4

62.6 ± 1.8

69.8 ± 2.2

81.0 ± 7.6

<0.0001

Age (years)

57.4 ± 12.3

62.4 ± 15.2

61.6 ± 13.0

61.9 ± 15.8

62.1 ± 15.5

0.96

Schooling (years)

8.3 ± 3.5

8.5 ± 3.9

7.9 ± 3.3

8.3 ± 3.3

7.9 ± 3.2

0.18

Systolic BP (mmHg)§

153.6 ± 19.9

151.5 ± 17.8

151.3 ± 20.1

153.8 ± 20.5

157.7 ± 20.5

<0.01

Diastolic BP (mmHg)§

89.7 ± 9.2

87.4 ± 8.2

88.9 ± 9.5

91.1 ± 9.2

91.3 ± 9.3

<0.0001

Body mass index (kg/m2)*

27.3 ± 4.4

27.0 ± 4.0

27.5 ± 4.7

27.6 ± 4.9

26.8 ± 3.8

0.16

Cigarettes/day in smokers

12.3 [10.3 - 13.6]

11.6 [8.6 - 14.5]

10.5 [7.0 - 14.2]

13.6 [10.4 - 16.8]

12.2 [8.4 - 16.0]

0.58

Ethanol intake (g/day)

47.2 [44.2 - 50.3]

47.9 [41.7 - 54.1]

47.4 [41.9 - 53.0]

45.6 [39.8 - 51.4]

47.9 [41.0 - 54.7]

0.95

Caffeine intake (mmol/day)

1.00 ± 0.68

1.02 ± 0.70

1.04 ± 0.66

0.90 ± 0.63

1.03 ± 0.70

0.11

Serum glucose (mmol/l)

5.41 ± 1.03

5.23 ± 0.78

5.40 ± 1.07

5.44 ± 1.03

5.58 ± 1.17

<0.01

Serum uric acid (µmol/l)

305.2 ± 78.0

304.4 ± 72.8

307.6 ± 79.9

297.7 ± 81.3

311.2 ± 80.7

0.33

LDL serum cholesterol (mmol/l)

3.71 ± 0.93

3.67 ± 0.90

3.79 ± 0.92

3.68 ± 0.93

3.72 ± 0.97

0.57

Fish intake (g/week)

100.4 ± 115.3

105.3 ± 109.2

109.0 ± 122.4

98.5 ± 132.0

89.0 ± 94.8

0.31

Glucose intake (g/week)

906.7 ± 380.7

914.1 ± 393.5

897.0 ± 408.0

905.4 ± 368.1

910.3 ± 354.6

0.99

Lipid intake (g/week)

548.1 ± 256.2

575.7 ± 261.3

554.8 ± 246.7

525.5 ± 252.5

536.5 ± 263.0

0.26

Categorical variables

Males, n (%)

427 (51.3)

125 (60.1)

116 (56.0)

98 (47.1)

88 (42.3)

<0.0001

Treatment of HT, n (%)

367 (44.2)

84 (40.4)

91 (44.0)

97 (46.6)

95 (45.7)

0.59

Smokers, n (%)

98 (11.2)

26 (12.5)

26 (12.5)

26 (12.5)

20 (9.6)

0.73

Drinkers, n (%)

525 (63.2)

140 (67.3)

143 (69.1)

120 (57.7)

122 (58.7)

0.03

Diabetics, n (%)

50 (6.0)

6 (2.9)

11 (5.3)

15 (7.2)

18 (8.7)

0.08