COMPARISM of PARAMETERS BETWEEN RADIOTHERAPY, RADIOSURGERY AND RADIOLYSIS | |||
PARAMETERS | RADIOTHERAPY | RADIO-SURGERY | RADIOLYSIS |
Objective | Tumor regression | Aneurismal fibrosis | Regression of keloidal mass |
Target cell tissue | Malignant cells | Aneurysmal walls | Keloidal collagen |
| Primary target |
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| Blood vessel |
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| Secondary target |
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BED of target cells/tissues | Low-normoxic | High | Not applicable |
| High Hypoxic | Connective tissue | Biologically innate |
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| Ground substances |
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Alpha/beta of targeted cells/tissue | Dependent | Independent | Independent |
Oxygenation | Dependent | Independent | Independent |
Cycling fraction | Dependent | Independent | Independent |
Fractionation | Dependent | Independent (?) | Independent |
Fraction size | Dependent | Dependent | Independent |
Impact of quality radiation | Dependent | No data | No data |
Impact of radio-sensitizers | Positive on hypoxic cells | No data | No data |
End point | Tumor resolution | Obliteration of aneurysmal cavity | 1). Inhibition of post-operative recurrence 2). Keloid resolution |