Treatment

Dose (mg/kg)

Licking of the hind paw

Early phase

% of inhibition

Late phase

% of inhibition

Control

0.1 mL/mouse

66.40 ± 2.09

0.00

35.00 ± 1.61

0.00

Diclofenac sodium

10

26.00 ± 0.71**

60.84

9.60 ± 0.93**

72.57

MEDM

200

52.60 ± 3.01**

20.78

30.40 ± 1.75**

13.14

MEDM

400

36.20 ± 1.39**

45.48

17.40 ± 1.12**

50.28

MEDM

600

28.60 ± 0.93**

56.93

11.60 ± 1.12**

66.85