Treatment | Mean Rectal Temperature (˚C) and % Reduction in Body Temperature of Rats | |||||||
Group BBT | 0 h | 0.5 h | 1 h | 1.5 h | 2 h | 3 h | 4 h | |
DW 10 mL/kg (NC) | 37.08 ± 0.17 | 38.06 ± 0.11 | 38.24 ± 0.20 | 38.30 ± 0.30 | 37.68 ± 0.45 | 37.78 ± 0.16 | 37.50 ± 0.54 | 37.82 ± 0.24 |
PBAE 100 mg/kg | 37.00 ± 0.18 | 38.02 ± 0.15 | 38.68 ± 0.31 (-)a | 37.92 ± 0.27 (0.99)a | 37.92 ± 0.30 (-)a | 37.92 ± 0.39 (-)a | 37.56 ± 0.20 (-)a | 37.68 ± 0.20 (0.37)a |
PBAE 200 mg/kg | 36.74 ± 0.14 | 37.98 ± 0.07 | 37.64 ± 0.27 (1.57)a | 37.86 ± 0.10 (1.15)a | 37.36 ± 0.32 (0.85)a | 37.42 ± 0.24 (0.95)a | 37.92 ± 0.10 (-)a | 37.90 ± 0.08 (-)a |
PBAE 400 mg/kg | 36.74 ± 0.05 | 37.86 ± 0.16 | 38.08 ± 0.32 (0.42)a | 38.06 ± 0.10 (0.63)a | 37.74 ± 0.19 (-)a | 37.56 ± 0.40 (0.58)a | 37.32 ± 0.36 (0.48)a | 37.86 ± 0.20 (-)a |
PCM 20 mg/kg (PC) | 37.16 ± 0.15 | 38.22 ± 0.16 | 38.10 ± 0.22 (0.37)a | 37.12 ± 0.17* (3.08)a | 36.50 ± 0.16* (3.13)a | 35.46 ± 0.25* (6.14)a | 35.28 ± 0.19* (5.92)a | 34.88 ± 0.25*(7.77)a |