Treatment

Mean Rectal Temperature (˚C) and % Reduction in Body Temperature of Rats

Group BBT

0 h

0.5 h

1 h

1.5 h

2 h

3 h

4 h

DW 10 mL/kg (NC)

37.08 ± 0.17

38.06 ± 0.11

38.24 ± 0.20

38.30 ± 0.30

37.68 ± 0.45

37.78 ± 0.16

37.50 ± 0.54

37.82 ± 0.24

PBAE 100 mg/kg

37.00 ± 0.18

38.02 ± 0.15

38.68 ± 0.31

(-)^a

37.92 ± 0.27

(0.99)^a

37.92 ± 0.30

(-)^a

37.92 ± 0.39

(-)^a

37.56 ± 0.20

(-)^a

37.68 ± 0.20

(0.37)^a

PBAE 200 mg/kg

36.74 ± 0.14

37.98 ± 0.07

37.64 ± 0.27

(1.57)^a

37.86 ± 0.10

(1.15)^a

37.36 ± 0.32

(0.85)^a

37.42 ± 0.24

(0.95)^a

37.92 ± 0.10

(-)^a

37.90 ± 0.08

(-)^a

PBAE 400 mg/kg

36.74 ± 0.05

37.86 ± 0.16

38.08 ± 0.32

(0.42)^a

38.06 ± 0.10

(0.63)^a

37.74 ± 0.19

(-)^a

37.56 ± 0.40

(0.58)^a

37.32 ± 0.36

(0.48)^a

37.86 ± 0.20

(-)^a

PCM 20 mg/kg (PC)

37.16 ± 0.15

38.22 ± 0.16

38.10 ± 0.22

(0.37)^a

37.12 ± 0.17*

(3.08)^a

36.50 ± 0.16*

(3.13)^a

35.46 ± 0.25*

(6.14)^a

35.28 ± 0.19*

(5.92)^a

34.88 ± 0.25*(7.77)^a