System organ class

Number of sheet

Frequency (%)

Skin and subcutaneous tissue disorders

147

45.7

General disorders and administration site conditions

96

29.8

Nervous system disorders

55

17.1

Gastro-intestinal disorders

41

12.7

Musculoskeletal and systemic disorders

25

7.8

Eye disorders

17

5.3

Renal and urinary disorders

16

5.0

Disorders of reproductive organs and breast

13

4.0

Immune system disorders

11

3.4

Respiratory, thoracic and mediastinal disorders

9

2.8