Conc

(% w/v)

log Partition Coefficient (mean ± SD^*)

log Dermal Permeability Coefficient

Tween 20

Tween 80

Sodium lauryl

sulfate

Sodium

cholate

Cetrimide

Tween

20

Tween

20

Sodium lauryl

sulfate

Sodium

cholate

Cetrimide

0.0

2.7680

2.7680

2.7680

2.7680

2.7680

−2.3790

−2.3790

2.7680

−2.3790

−2.3790

0.05

2.2270

2.1999

2.3169

2.1536

1.9292

−2.7633

−2.7825

−2.6994

−2.8154

−2.9747

0.10

2.2158

2.1840

1.9056

1.9499

1.6450

−2.7712

−2.7938

−2.9915

−2.9600

−3.1765

0.20

2.0665

1.8701

1.8080

1.8283

1.4814

−2.8772

−3.0167

−3.0463

−3.0463

−3.2926

0.50

1.7364

1.6427

1.5864

1.5534

1.2144

−3.1116

−3.1781

−3.2181

−3.2415

−3.4822

1.00

1.6538

1.5515

1.4713

1.3528

1.0522

−3.1702

−3.2429

−3.2998

−3.3839

−3.5974

2.00

1.5384

1.3966

1.2700

1.2465

0.9141

−3.2522

−3.3528

−3.4427

−3.4594

−3.6954