Conc

(% w/v)

Log Partition Coefficient (mean ± SD)

Log Dermal Permeability Coefficient

Glycerol

Propylene

glycol

Ethanol

Polyethylene

glycol 400

Glycerol

Propylene

glycol

Ethanol

Polyethylene

glycol 400

0.0

2.7680 ± 0.036

2.768 ± 0.036

2.768 ± 0.036

2.768 ± 0.036

−2.379

−2.379

−2.379

−2.379

5.0

2.5709 ± 0.041

2.5327 ± 0.016

2.3712 ± 0.048

1.9977 ± 0.038

−2.5191

−2.5462

−2.6609

−2.9261

10.0

2.5234 ± 0.007

2.4627 ± 0.031

2.2325 ± 0.026

1.5629 ± 0.029

−2.5528

−2.5959

−2.7594

−3.2348

15.0

2.4707 ± 0.011

2.0623 ± 0.025

1.9499 ± 0.021

1.4026 ± 0.002

−2.5902

−2.8802

−2.9600

−3.3486

20.0

2.3368 ± 0.063

2.0414 ± 0.021

1.7043 ± 0.008

1.2004 ± 0.006

−2.6853

−2.8950

−3.1344

−3.4921

25.0

2.1944 ± 0.056

1.9941 ± 0.013

1.3671 ± 0.029

0.9841 ± 0.015

−2.7864

−2.9286

−3.3738

−3.6457