| Visit | Statistic | Net % positive of each functional response of CD4+ T cells | Net % positive of each functional response of CD8+ T cells | ||||||||
| CD107a/b | IFN-g | MIP-1β | IL-2 | TNF-α | CD107a/b | IFN-g | MIP-1β | IL-2 | TNF-α | ||
| Pre-vac | Mean ± SD | 0.002 ± 0.004 | 0.000 ± 0.000 | 0.000 ± 0.000 | 0.000 ± 0.000 | 0.006 ± 0.013 | 0.000 ± 0.000 | 0.010 ± 0.022 | 0.000 ± 0.000 | 0.002 ± 0.004 | 0.000 ± 0.000 |
| Median (min - max) | 0.00 (0.00 - 0.01) | 0.00 (0.00 - 0.00) | 0.00 (0.00 - 0.00) | 0.00 (0.00 - 0.00) | 0.00 (0.00 - 0.03) | 0.00 (0.00 - 0.00) | 0.00 (0.00 - 0.05) | 0.00 (0.00 - 0.00) | 0.00 (0.00 - 0.01) | 0.00 (0.00 - 0.00) | |
| 1 month | Mean ± SD | 1.028 ± 1.171 | 0.342 ± 0.759 | 2.954 ± 1.218 | 0.560 ± 1.230 | 2.250 ± 3.363 | 30.620 ± 19.545 | 5.502 ± 7.423 | 24.128 ± 20.056 | 0.576 ± 0.860 | 3.286 ± 4.052 |
| Median (min - max) | 0.33 (0.06 - 2.59) | 0.00 (0.00 - 1.70) | 3.38 (1.27 - 4.28) | 0.00 (0.00 - 2.76) | 1.13 (0.00 - 8.19) | 24.15 (11.41 - 57.07) | 2.26 (0.90 - 18.49) | 33.24 (1.27 - 42.91) | 0.15 (0.02 - 2.08) | 1.40 (0.58 - 10.40) | |
| p-value | 0.122 | 0.371 | 0.006 | 0.366 | 0.211 | 0.025 | 0.174 | 0.055 | 0.21 | 0.144 | |
| 3 months | Mean ± SD | 0.606 ± 0.579 | 0.268 ± 0.588 | 2.670 ± 1.144 | 0.138 ± 0.303 | 1.160 ± 1.926 | 28.576 ± 15.683 | 5.022 ± 4.295 | 27.624 ± 22.110 | 0.168 ± 0.263 | 2.644 ± 1.996 |
| Median (min - max) | 0.53 (0.12 - 1.54) | 0.01 (0.00 - 1.32) | 2.38 (1.68 - 4.65) | 0.00 (0.00 - 0.68) | 0.42 (0.00 - 4.57) | 23.80 (8.67 - 48.88) | 3.45 (0.73 - 10.77) | 36.60 (1.06 - 48.37) | 0.02 (0.01 - 0.62) | 1.77 (0.84 - 5.61) | |
| p-value | 0.081 | 0.366 | 0.006 | 0.366 | 0.252 | 0.015 | 0.06 | 0.049 | 0.231 | 0.041 | |
| 6 months | Mean ± SD | 0.364 ± 0.385 | 0.238 ± 0.450 | 2.906 ± 1.964 | 0.070 ± 0.105 | 1.408 ± 1.349 | 23.886 ± 13.982 | 3.872 ± 3.132 | 22.642 ± 18.693 | 0.096 ± 0.116 | 2.118 ± 1.467 |
| Median (min - max) | 0.33 (0.06 - 1.01) | 0.05 (0.00 - 1.04) | 2.11 (1.31 - 5.85) | 0.03 (0.00 - 0.25) | 1.03 (0.00 - 3.44) | 27.91 (5.76 - 42.37) | 4.19 (0.32 - 8.44) | 32.08 (1.32 - 43.14) | 0.03 (0.00 - 0.28) | 2.08 (0.66 - 3.75) | |
| p-value | 0.103 | 0.302 | 0.03 | 0.209 | 0.081 | 0.019 | 0.051 | 0.054 | 0.134 | 0.032 | |
| 12 months | Mean ± SD | 0.502 ± 0.632 | 0.098 ± 0.120 | 2.598 ± 3.197 | 0.020 ± 0.045 | 0.668 ± 0.954 | 17.032 ± 14.319 | 1.364 ± 0.990 | 20.742 ± 19.239 | 0.084 ± 0.061 | 1.316 ± 0.869 |
| Median (min - max) | 0.20 (0.01 - 1.51) | 0.07 (0.00 - 0.29) | 1.17 (0.54 - 8.16) | 0.00 (0.00 - 0.10) | 0.38 (0.00 - 2.30) | 20.45 (0.23 - 37.09) | 1.06 (0.16 - 2.79) | 27.76 (0.14 - 43.81) | 0.09 (0.00 - 0.15) | 1.31 (0.14 - 2.55) | |
| p-value | 0.152 | 0.143 | 0.143 | 0.374 | 0.191 | 0.056 | 0.038 | 0.073 | 0.034 | 0.028 | |