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Statistic

Net % positive of each functional response of CD4+ T cells

Net % positive of each functional response of CD8+ T cells

CD107a/b

IFN-g

MIP-1β

IL-2

TNF-α

CD107a/b

IFN-g

MIP-1β

IL-2

TNF-α

Pre-vac

Mean ± SD

0.002 ± 0.004

0.000 ± 0.000

0.000 ± 0.000

0.000 ± 0.000

0.006 ± 0.013

0.000 ± 0.000

0.010 ± 0.022

0.000 ± 0.000

0.002 ± 0.004

0.000 ± 0.000

Median (min - max)

0.00

(0.00 - 0.01)

0.00 (0.00 - 0.00)

0.00 (0.00 - 0.00)

0.00 (0.00 - 0.00)

0.00 (0.00 - 0.03)

0.00 (0.00 - 0.00)

0.00 (0.00 - 0.05)

0.00 (0.00 - 0.00)

0.00 (0.00 - 0.01)

0.00 (0.00 - 0.00)

1 month

Mean ± SD

1.028 ± 1.171

0.342 ± 0.759

2.954 ± 1.218

0.560 ± 1.230

2.250 ± 3.363

30.620 ± 19.545

5.502 ± 7.423

24.128 ± 20.056

0.576 ± 0.860

3.286 ± 4.052

Median (min - max)

0.33

(0.06 - 2.59)

0.00 (0.00 - 1.70)

3.38 (1.27 - 4.28)

0.00 (0.00 - 2.76)

1.13 (0.00 - 8.19)

24.15 (11.41 - 57.07)

2.26 (0.90 - 18.49)

33.24 (1.27 - 42.91)

0.15 (0.02 - 2.08)

1.40 (0.58 - 10.40)

p-value

0.122

0.371

0.006

0.366

0.211

0.025

0.174

0.055

0.21

0.144

3 months

Mean ± SD

0.606 ± 0.579

0.268 ± 0.588

2.670 ± 1.144

0.138 ± 0.303

1.160 ± 1.926

28.576 ± 15.683

5.022 ± 4.295

27.624 ± 22.110

0.168 ± 0.263

2.644 ± 1.996

Median (min - max)

0.53 (0.12 - 1.54)

0.01 (0.00 - 1.32)

2.38 (1.68 - 4.65)

0.00 (0.00 - 0.68)

0.42 (0.00 - 4.57)

23.80 (8.67 - 48.88)

3.45 (0.73 - 10.77)

36.60 (1.06 - 48.37)

0.02 (0.01 - 0.62)

1.77 (0.84 - 5.61)

p-value

0.081

0.366

0.006

0.366

0.252

0.015

0.06

0.049

0.231

0.041

6 months

Mean ± SD

0.364 ± 0.385

0.238 ± 0.450

2.906 ± 1.964

0.070 ± 0.105

1.408 ± 1.349

23.886 ± 13.982

3.872 ± 3.132

22.642 ± 18.693

0.096 ± 0.116

2.118 ± 1.467

Median (min - max)

0.33 (0.06 - 1.01)

0.05 (0.00 - 1.04)

2.11 (1.31 - 5.85)

0.03 (0.00 - 0.25)

1.03 (0.00 - 3.44)

27.91 (5.76 - 42.37)

4.19 (0.32 - 8.44)

32.08 (1.32 - 43.14)

0.03 (0.00 - 0.28)

2.08 (0.66 - 3.75)

p-value

0.103

0.302

0.03

0.209

0.081

0.019

0.051

0.054

0.134

0.032

12 months

Mean ± SD

0.502 ± 0.632

0.098 ± 0.120

2.598 ± 3.197

0.020 ± 0.045

0.668 ± 0.954

17.032 ± 14.319

1.364 ± 0.990

20.742 ± 19.239

0.084 ± 0.061

1.316 ± 0.869

Median (min - max)

0.20 (0.01 - 1.51)

0.07 (0.00 - 0.29)

1.17 (0.54 - 8.16)

0.00 (0.00 - 0.10)

0.38 (0.00 - 2.30)

20.45 (0.23 - 37.09)

1.06 (0.16 - 2.79)

27.76 (0.14 - 43.81)

0.09 (0.00 - 0.15)

1.31 (0.14 - 2.55)

p-value

0.152

0.143

0.143

0.374

0.191

0.056

0.038

0.073

0.034

0.028