*Treatment Options | Day 0 | Control | Day 5 | Control | Day 10 | Control | Day 15 | Control | Day 20 | Control | Day 25 | Control |
A1 | 334.71 ± 0.77 | 247.94 ± 0.23 | 253.57 ± 0.34 | 187.83 ± 0.44 | 192.10 ± 0.22 | 142.30 ± 0.44 | 145.53 ± 0.65 | 107.80 ± 0.33 | 108.63 ± 0.30 | 111.69 ± 0.16 | 101.00 ± 0.56 | 111.00 ± 0.23 |
B | 340.35 ± 0.43 | 247.94 ± 0.50 | 257.84 ± 0.65 | 187.83 ± 0.54 | 195.33 ± 0.88 | 142.30 ± 0.88 | 147.98 ± 0.65 | 107.80 ± 0.67 | 135.15 ± 0.16 | 111.69 ± 0.30 | 132.45 ± 0.76 | 111.00 ± 0.60 |
E | 323.44 ± 0.76 | 247.94 ± 0.43 | 245.03 ± 0.15 | 187.83 ± 0.30 | 185.63 ± 0.40 | 142.30 ± 0.71 | 140.63 ± 0.49 | 107.80 ± 0.81 | 130.56 ± 0.30 | 111.69 ± 0.68 | 113.15 ± 0.23 | 111.00 ± 0.11 |
K | 353.87 ± 0.53 | 247.94 ± 0.94 | 268.09 ± 0.68 | 187.83 ± 0.87 | 203.10 ± 0.30 | 142.30 ± 0.42 | 153.86 ± 0.86 | 107.80 ± 0.17 | 114.24 ± 0.14 | 111.69 ± 0.60 | 107.33 ± 0.74 | 111.00 ± 0.40 |
A1 + B | 386.56 ± 0.19 | 247.94 ± 0.18 | 292.85 ± 0.18 | 187.83 ± 0.18 | 221.85 ± 0.58 | 142.30 ± 0.19 | 168.07 ± 0.94 | 107.80 ± 0.77 | 125.46 ± 0.28 | 111.69 ± 0.21 | 122.27 ± 0.90 | 111.00 ± 0.70 |
A1 + E | 351.62 ± 0.65 | 247.94 ± 0.49 | 266.38 ± 0.18 | 187.83 ± 0.76 | 201.80 ± 0.27 | 142.30 ± 0.20 | 152.88 ± 0.17 | 107.80 ± 0.39 | 121.89 ± 0.60 | 111.69 ± 0.15 | 118.20 ± 0.16 | 111.00 ± 0.49 |
A1 + K | 436.14 ± 0.89 | 247.94 ± 0.43 | 330.41 ± 0.87 | 187.83 ± 0.76 | 250.31 ± 0.65 | 142.30 ± 0.42 | 189.63 ± 0.87 | 107.80 ± 0.43 | 113.73 ± 0.65 | 111.69 ± 0.71 | 111.00 ± 0.21 | 111.00 ± 0.65 |
B + E | 375.29 ± 0.65 | 247.94 ± 0.42 | 284.31 ± 0.76 | 187.83 ± 0.67 | 215.38 ± 0.78 | 142.30 ± 0.45 | 163.17 ± 0.78 | 107.80 ± 0.23 | 134.64 ± 0.89 | 111.69 ± 0.83 | 115.75 ± 0.42 | 111.00 ± 0.76 |
B + K | 451.92 ± 0.56 | 247.74 ± 0.91 | 342.36 ± 0.67 | 187.83 ± 0.91 | 259.37 ± 0.78 | 142.30 ± 0.34 | 196.49 ± 0.78 | 107.80 ± 0.12 | 120.36 ± 0.43 | 111.69 ± 0.78 | 111.90 ± 0.67 | 111.00 ± 0.12 |
E + K | 396.70 ± 0.13 | 247.94 ± 0.12 | 300.53 ± 0.39 | 187.83 ± 0.83 | 227.67 ± 0.22 | 142.30 ± 0.39 | 172.48 ± 0.39 | 107.80 ± 0.29 | 129.54 ± 0.19 | 111.69 ± 0.13 | 116.00 ± 0.22 | 111.00 ± 0.32 |
A1 + E + K | 482.35 ± 0.82 | 247.94 ± 0.24 | 365.42 ± 0.64 | 187.83 ± 0.87 | 276.83 ± 0.76 | 142.30 ± 0.24 | 209.72 ± 0.27 | 107.80 ± 0.47 | 124.44 ± 0.45 | 111.69 ± 0.67 | 122.13 ± 0.32 | 111.00 ± 0.19 |
B + E + K | 447.41 ± 0.14 | 247.94 ± 0.47 | 338.95 ± 0.59 | 187.83 ± 0.79 | 256.78 ± 0.65 | 142.30 ± 0.47 | 194.53 ± 0.34 | 107.80 ± 0.99 | 132.09 ± 0.23 | 111.69 ± 0.11 | 114.71 ± 0.14 | 111.00 ± 0.12 |
A1 + B + E | 414.73 ± 0.17 | 247.94 ± 0.49 | 314.19 ± 0.19 | 187.83 ± 0.66 | 238.02 ± 0.39 | 142.30 ± 0.43 | 180.32 ± 0.23 | 107.80 ± 0.87 | 127.50 ± 0.54 | 111.69 ± 0.12 | 125.30 ± 0.55 | 111.00 ± 0.65 |
A1 + B + K | 458.68 ± 0.78 | 247.94 ± 0.62 | 347.49 ± 0.61 | 187.83 ± 0.78 | 268.25 ± 0.56 | 142.30 ± 0.78 | 199.43 ± 0.66 | 107.80 ± 0.47 | 133.11 ± 0.56 | 111.69 ± 0.62 | 114.00 ± 0.61 | 111.00 ± 0.55 |
A1 + B + E + K | 499.25 ± 0.73 | 247.94 ± 0.73 | 239.91 ± 0.73 | 187.83 ± 0.32 | 283.53 ± 0.51 | 142.30 ± 0.48 | 217.07 ± 0.54 | 107.80 ± 0.17 | 130.05 ± 0.48 | 111.69 ± 0.65 | 74.12 ± 0.54 | 111.00 ± 0.29 |
A2 | 316.68 ± 0.76 | 247.94 ± 0.66 | 239.73 ± 0.32 | 187.83 ± 0.82 | 181.75 ± 0.87 | 142.30 ± 0.66 | 137.69 ± 0.53 | 107.80 ± 0.64 | 121.89 ± 0.87 | 111.69 ± 0.64 | 62.30 ± 0.53 | 111.00 ± 0.18 |
P | 303.16 ± 0.53 | 247.94 ± 0.74 | 229.67 ± 0.83 | 187.83 ± 0.53 | 173.99 ± 0.25 | 142.30 ± 0.83 | 131.81 ± 0.38 | 107.80 ± 0.53 | 230.93 ± 0.22 | 111.69 ± 0.66 | 120.00 ± 0.46 | 111.00 ± 0.53 |
A2 + P | 343.73 ± 0.46 | 247.94 ± 0.78 | 260.40 ± 0.56 | 187.83 ± 0.42 | 197.27 ± 0.54 | 142.30 ± 0.42 | 149.40 ± 0.93 | 107.80 ± 0.39 | 135.15 ± 0.93 | 111.69 ± 0.48 | 134.70 ± 0.42 | 111.00 ± 0.39 |