*Treatment Options

Day 0

Control

Day 5

Control

Day 10

Control

Day 15

Control

Day 20

Control

Day 25

Control

A1

297.00 ± 0.22

220.00 ± 0.34

213.00 ± 0.11

219.00 ± 0.56

683.90 ± 0.54

505.99 ± 0.34

517.49 ± 0.53

383.33 ± 0.54

392.04 ± 0.19

290.40 ± 0.70

133.45 ± 0.45

326.00 ± 0.91

B

302.00 ± 0.98

220.00 ± 0.70

265.00 ± 0.77

219.00 ± 0.34

694.59 ± 0.90

505.99 ± 0.75

526.20 ± 0.87

383.33 ± 0.54

398.64 ± 0.32

290.40 ± 0.45

153.50 ± 0.88

326.00 ± 0.43

E

287.00 ± 0.78

220.00 ± 0.67

256.00 ± 0.34

219.00 ± 0.20

219.00 ± 0.20

505.99 ± 0.51

500.07 ± 0.89

383.33 ± 0.19

378.84 ± 0.84

290.40 ± 0.29

135.00 ± 0.35

326.00 ± 0.27

K

314.00 ± 0.31

220.00 ± 0.20

224.00 ± 0.24

219.00 ± 0.19

722.19 ± 0.22

505.99 ± 0.49

547.11 ± 0.47

383.33 ± 0.38

414.48 ± 0.14

290.40 ± 0.34

164.03 ± 0.16

326.00 ± 0.75

A1 + B

343.00 ± 0.76

220.00 ± 0.19

246.00 ± 0.12

219.00 ± 0.18

788.89 ± 0.81

505.99 ± 0.14

597.64 ± 0.80

383.33 ± 0.19

452.76 ± 0.19

290.40 ± 0.19

225.4 ± 0.39

326.00 ± 0.19

A1 + E

312.00 ± 0.29

220.00 ± 0.19

239.00 ± 0.28

219.00 ± 0.66

717.59 ± 0.18

505.99 ± 0.29

543.63 ± 0.39

383.33 ± 0.19

411.84 ± 0.29

290.40 ± 0.59

152.16 ± 0.28

326.00 ± 0.29

A1 + K

387.00 ± 0.23

220.00 ± 0.56

223.00 ± 0.75

219.00 ± 0.32

890.09 ± 0.71

505.99 ± 0.89

674.31 ± 0.71

383.33 ± 0.83

510.84 ± 0.71

290.40 ± 0.89

183.23 ± 0.67

326.00 ± 0.89

B + E

333.00 ± 0.45

220.00 ± 0.50

264.00 ± 0.19

219.00 ± 0.34

765.89 ± 0.34

505.99 ± 0.83

580.22 ± 0.67

383.33 ± 0.83

439.56 ± 0.76

290.40 ± 0.19

141.34 ± 0.76

326.00 ± 0.78

B + K

401.00 ± 0.31

220.00 ± 0.34

236.00 ± 0.16

219.00 ± 0.34

922.29 ± 0.12

505.99 ± 0.50

698.70 ± 0.39

383.33 ± 0.11

529.32 ± 0.78

290.40 ± 0.42

101.10 ± 0.45

326.00 ± 0.50

E + K

352.00 ± 0.76

220.00 ± 0.77

254.00 ± 0.16

219.00 ± 0.40

809.59 ± 0.90

505.99 ± 0.68

613.32 ± 0.37

383.33 ± 0.15

464.64 ± 0.55

290.40 ± 0.38

141.52 ± 0.28

326.00 ± 0.66

A1 + E + K

428.00 ± 0.39

220.00 ± 0.34

244.00 ± 0.23

219.00 ± 0.45

984.39 ± 0.39

505.99 ± 0.19

745.75 ± 0.75

383.33 ± 0.33

564.96 ± 0.69

290.40 ± 0.29

621.30 ± 0.32

326.00 ± 0.26

B +

E + K

397.00 ± 0.65

220.00 ± 0.20

259.00 ± 0.56

219.00 ± 0.18

913.09 ± 0.30

505.99 ± 0.50

691.73 ± 0.68

383.33 ± 0.33

524.04 ± 0.24

290.40 ± 0.91

911.00 ± 0.17

326.00 ± 0.62

A1 + B + E

368.00 ± 0.86

220.00 ± 0.20

250.00 ± 0.50

219.00 ± 0.18

846.39 ± 0.46

505.99 ± 0.50

641.20 ± 0.41

383.33 ± 0.45

485.76 ± 0.57

290.40 ± 0.90

853.20 ± 0.54

326.00 ± 0.62

A1 + B + K

407.00 ± 0.62

220.00 ± 0.61

261.00 ± 0.38

219.00 ± 0.55

936.09 ± 0.47

505.99 ± 0.61

709.16 ± 0.55

383.33 ± 0.43

537.24 ± 00.61

290.40 ± 0.66

781.00 ± 0.23

326.00 ± 0.78

A1 + B

+ E + K

443.00 ± 0.66

220.00 ± 0.48

239.00 ± 0.32

219.00 ± 0.48

101.88 ± 0.97

505.99 ± 0.54

771.88 ± 0.66

383.33 ± 0.65

584.76 ± 0.54

290.40 ± 0.32

60.00 ± 0.65

326.00 ± 0.48

A2

281.00 ± 0.44

220.00 ± 0.53

239.00 ± 0.76

219.00 ± 0.44

646.29 ± 0.66

505.99 ± 0.82

489.61 ± 0.87

383.33 ± 0.76

370.92 ± 0.45

290.40 ± 0.66

533.00 ± 0.43

326.00 ± 0.53

P

269.00 ± 0.74

220.00 ± 0.73

243.00 ± 0.64

219.00 ± 0.59

618.69 ± 0.74

505.99 ± 0.53

468.71 ± 0.64

383.33 ± 0.74

355.08 ± 0.98

290.40 ± 0.74

244.71 ± 0.38

326.00 ± 0.64

A2 + P

305.00 ± 0.92

220.00 ± 0.62

265.00 ± 0.76

219.00 ± 0.83

701.49 ± 0.63

505.99 ± 0.51

531.43 ± 0.42

383.33 ± 0.56

402.60 ± 0.75

290.40 ± 0.42

225.62 ± 0.51

326.00 ± 0.83