*Treatment Options | Day 0 | Control | Day 5 | Control | Day 10 | Control | Day 15 | Control | Day 20 | Control | Day 25 | Control |
A1 | 6.87 ± 0.12 | 6.98 ± 0.54 | 5.76 ± 0.77 | 6.95 ± 0.44 | 4.95 ± 0.35 | 6.67 ± 0.65 | 4.26 ± 0.64 | 6.41 ± 0.14 | 3.66 ± 0.80 | 6.15 ± 0.22 | 3.58 ± 0.55 | 6.40 ± 0.44 |
B | 6.64 ± 0.68 | 6.98 ± 0.89 | 5.63 ± 0.30 | 6.95 ± 0.67 | 4.84 ± 0.84 | 6.67 ± 0.88 | 4.16 ± 0.76 | 6.41 ± 0.12 | 3.58 ± 0.32 | 6.15 ± 0.50 | 3.52 ± 0.33 | 6.11 ± 0.65 |
E | 6.79 ± 0.65 | 6.98 ± 0.75 | 5.58 ± 0.64 | 6.95 ± 0.80 | 4.88 ± 0.45 | 6.67 ± 0.29 | 4.20 ± 0.43 | 6.41 ± 0.39 | 3.61 ± 0.38 | 6.15 ± 0.16 | 3.56 ± 0.57 | 6.11 ± 0.16 |
K | 6.66 ± 0.67 | 6.98 ± 0.98 | 5.72 ± 0.52 | 6.95 ± 0.34 | 4.92 ± 0.92 | 6.67 ± 0.65 | 4.23 ± 0.43 | 6.41 ± 0.42 | 3.64 ± 0.65 | 6.15 ± 0.22 | 3.60 ± 0.89 | 6.11 ± 0.43 |
A1 + B | 6.59 ± 0.25 | 6.98 ± 0.18 | 5.59 ± 0.62 | 6.95 ± 0.59 | 4.81 ± 0.51 | 6.67 ± 0.31 | 4.13 ± 0.43 | 6.41 ± 0.12 | 3.56 ± 0.49 | 6.15 ± 0.30 | 3.45 ± 0.31 | 6.11 ± 0.23 |
A1 + E | 6.74 ± 0.19 | 6.95 ± 0.19 | 5.47 ± 0.18 | 6.95 ± 0.60 | 4.70 ± 0.66 | 6.67 ± 0.39 | 4.05 ± 0.67 | 6.41 ± 0.64 | 3.48 ± 0.23 | 6.15 ± 0.70 | 3.48 ± 0.45 | 6.11 ± 0.46 |
A1 + K | 6.87 ± 0.87 | 6.98 ± 0.17 | 5.54 ± 0.43 | 6.95 ± 0.22 | 4.76 ± 0.36 | 6.67 ± 0.43 | 4.10 ± 0.42 | 6.41 ± 0.67 | 3.52 ± 0.36 | 6.15 ± 0.56 | 3.48 ± 0.42 | 6.11 ± 0.43 |
B + E | 6.64 ± 0.34 | 6.98 ± 0.23 | 5.49 ± 0.24 | 6.95 ± 0.23 | 4.72 ± 0.77 | 6.67 ± 0.24 | 4.06 ± 0.16 | 6.41 ± 0.24 | 3.49 ± 0.50 | 6.15 ± 0.34 | 3.45 ± 0.16 | 6.11 ± 0.45 |
B + K | 6.89 ± 0.91 | 6.00 ± 0.50 | 5.55 ± 0.67 | 6.95 ± 0.43 | 4.77 ± 0.39 | 6.67 ± 0.33 | 4.10 ± 0.31 | 6.41 ± 0.50 | 3.53 ± 0.76 | 6.15 ± 0.16 | 3.50 ± 0.83 | 6.11 ± 0.24 |
E + K | 6.46 ± 0.33 | 6.98 ± 0.56 | 5.46 ± 0.27 | 6.95 ± 0.30 | 4.70 ± 0.30 | 6.67 ± 0.19 | 4.04 ± 0.16 | 6.41 ± 0.29 | 3.47 ± 0.40 | 6.15 ± 0.12 | 3.41 ± 0.19 | 6.11 ± 0.39 |
A1 + E + K | 6.88 ± 0.29 | 6.98 ± 0.39 | 5.47 ± 0.30 | 6.95 ± 0.33 | 4.70 ± 0.50 | 6.67 ± 0.49 | 4.05 ± 0.18 | 6.41 ± 0.20 | 3.48 ± 0.18 | 6.15 ± 0.15 | 3.44 ± 0.39 | 6.11 ± 0.29 |
B + E + K | 6.54 ± 0.14 | 6.98 ± 0.14 | 5.35 ± 0.13 | 6.95 ± 0.97 | 4.60 ± 0.64 | 6.67 ± 0.66 | 3.96 ± 0.39 | 6.41 ± 0.41 | 3.40 ± 0.58 | 6.15 ± 0.33 | 3.36 ± 0.63 | 6.11 ± 0.12 |
A1 + B + E | 6.83 ± 0.38 | 6.98 ± 0.89 | 5.29 ± 0.53 | 6.95 ± 0.96 | 4.55 ± 0.99 | 6.67 ± 0.11 | 3.91 ± 0.76 | 6.41 ± 0.41 | 3.36 ± 0.33 | 6.15 ± 0.51 | 3.34 ± 0.43 | 6.11 ± 0.11 |
A1 + B + K | 6.76 ± 0.23 | 6.98 ± 0.27 | 5.41 ± 0.14 | 6.95 ± 0.23 | 4.65 ± 0.43 | 6.67 ± 0.14 | 4.00 ± 0.21 | 6.41 ± 0.27 | 3.44 ± 0.23 | 6.15 ± 0.21 | 3.42 ± 0.34 | 6.11 ± 0.27 |
A1 + B + E + K | 6.69 ± 0.21 | 6.98 ± 0.29 | 5.38 ± 0.73 | 6.95 ± 0.21 | 4.63 ± 0.09 | 6.67 ± 0.42 | 3.98 ± 0.17 | 6.41 ± 0.42 | 3.42 ± 0.21 | 6.15 ± 0.48 | 3.40 ± 0.42 | 6.11 ± 0.21 |
A2 | 6.77 ± 0.37 | 6.98 ± 0.34 | 5.57 ± 0.21 | 6.95 ± 0.37 | 4.79 ± 0.53 | 6.67 ± 0.21 | 4.12 ± 0.37 | 6.41 ± 0.18 | 3.54 ± 0.21 | 6.15 ± 0.37 | 3.50 ± 0.44 | 6.11 ± 0.37 |
P | 6.81 ± 0.42 | 6.98 ± 0.22 | 5.61 ± 0.38 | 6.95 ± 0.51 | 4.82 ± 0.42 | 6.67 ± 0.22 | 4.15 ± 0.32 | 6.41 ± 0.13 | 3.57 ± 0.42 | 6.15 ± 0.32 | 3.51 ± 0.22 | 6.11 ± 0.42 |
A2 + P | 6.75 ± 6.98 | 6.98 ± 0.19 | 5.42 ± 0.25 | 6.95 ± 0.11 | 4.66 ± 0.25 | 6.67 ± 0.56 | 4.01 ± 0.39 | 6.41 ± 0.25 | 3.45 ± 0.34 | 6.15 ± 0.11 | 3.44 ± 0.56 | 6.11 ± 0.25 |