*Treatment Options

Day 0

Control

Day 5

Control

Day 10

Control

Day 15

Control

Day 20

Control

Day 25

Control

A1

4.69 ± 0.84

8.58 ± 0.45

1.11 ± 0.12

7.99 ± 0.22

82.60 ± 0.32

5.25 ± 0.21

109.04 ± 0.75

3.45 ± 0.18

143.93 ± 0.40

2.26 ± 0.80

1.72 ± 0.38

1.70 ± 0.34

B

5.83 ± 0.23

8.58 ± 0.34

1.38 ± 0.20

7.99 ± 0.87

83.99 ± 0.76

5.25 ± 0.34

110.87 ± 0.32

3.45 ± 0.23

146.35 ± 0.45

2.26 ± 0.55

1.26 ± 0.39

1.70 ± 0.39

E

5.63 ± 0.65

8.58 ± 0.56

1.34 ± 0.25

7.99 ± 0.28

79.82 ± 0.23

5.25 ± 0.53

105.36 ± 0.61

3.45 ± 0.56

139.08 ± 0.39

2.26 ± 0.29

1.6 ± 0.19

1.70 ± 0.77

K

4.93 ± 0.49

8.58 ± 0.58

1.17 ± 0.17

7.99 ± 0.79

87.33 ± 0.33

5.25 ± 0.35

115.28 ± 0.15

3.45 ± 0.45

152.17 ± 0.78

2.26 ± 0.66

1.27 ± 0.80

1.70 ± 0.79

A1 + B

5.41 ± 0.31

8.58 ± 0.55

1.29 ± 0.19

7.99 ± 0.78

95.40 ± 0.15

5.25 ± 0.54

125.92 ± 0.91

3.45 ± 0.45

166.22 ± 0.29

2.26 ± 0.30

2.20 ± 0.19

1.70 ± 0.13

A1 + E

4.69 ± 0.84

8.58 ± 0.45

1.11 ± 0.12

7.99 ± 0.22

82.60 ± 0.32

5.25 ± 0.21

109.04 ± 0.75

3.45 ± 0.18

143.93 ± 0.40

2.26 ± 0.80

1.72 ± 0.38

1.70 ± 0.34

A1 + K

5.83 ± 0.23

8.58 ± 0.34

1.38 ± 0.20

7.99 ± 0.87

83.99 ± 0.76

5.25 ± 0.34

110.87 ± 0.32

3.45 ± 0.23

146.35 ± 0.45

2.26 ± 0.55

1.26 ± 0.39

1.70 ± 0.39

B + E

5.63 ± 0.65

8.58 ± 0.56

1.34 ± 0.25

7.99 ± 0.28

79.82 ± 0.23

5.25 ± 0.53

105.36 ± 0.61

3.45 ± 0.56

139.08 ± 0.39

2.26 ± 0.29

1.6 ± 0.19

1.70 ± 0.77

B + K

4.93 ± 0.49

8.58 ± 0.58

1.17 ± 0.17

7.99 ± 0.79

87.33 ± 0.33

5.25 ± 0.35

115.28 ± 0.15

3.45 ± 0.45

152.17 ± 0.78

2.26 ± 0.66

1.27 ± 0.80

1.70 ± 0.79

E + K

5.41 ± 0.31

8.58 ± 0.55

1.29 ± 0.19

7.99 ± 0.78

95.40 ± 0.15

5.25 ± 0.54

125.92 ± 0.91

3.45 ± 0.45

166.22 ± 0.29

2.26 ± 0.30

2.20 ± 0.19

1.70 ± 0.13

A1 + E + K

4.69 ± 0.84

8.58 ± 0.45

1.11 ± 0.12

7.99 ± 0.22

82.60 ± 0.32

5.25 ± 0.21

109.04 ± 0.75

3.45 ± 0.18

143.93 ± 0.40

2.26 ± 0.80

1.72 ± 0.38

1.70 ± 0.34

B + E + K

5.83 ± 0.23

8.58 ± 0.34

1.38 ± 0.20

7.99 ± 0.87

83.99 ± 0.76

5.25 ± 0.34

110.87 ± 0.32

3.45 ± 0.23

146.35 ± 0.45

2.26 ± 0.55

1.26 ± 0.39

1.70 ± 0.39

A1 + B + E

5.63 ± 0.65

8.58 ± 0.56

1.34 ± 0.25

7.99 ± 0.28

79.82 ± 0.23

5.25 ± 0.53

105.36 ± 0.61

3.45 ± 0.56

139.08 ± 0.39

2.26 ± 0.29

1.6 ± 0.19

1.70 ± 0.77

A1 + B + K

4.93 ± 0.49

8.58 ± 0.58

1.17 ± 0.17

7.99 ± 0.79

87.33 ± 0.33

5.25 ± 0.35

115.28 ± 0.15

3.45 ± 0.45

152.17 ± 0.78

2.26 ± 0.66

1.27 ± 0.80

1.70 ± 0.79

A1 + B + E + K

5.41 ± 0.31

8.58 ± 0.55

1.29 ± 0.19

7.99 ± 0.78

95.40 ± 0.15

5.25 ± 0.54

125.92 ± 0.91

3.45 ± 0.45

166.22 ± 0.29

2.26 ± 0.30

2.20 ± 0.19

1.70 ± 0.13

A2

4.69 ± 0.84

8.58 ± 0.45

1.11 ± 0.12

7.99 ± 0.22

82.60 ± 0.32

5.25 ± 0.21

109.04 ± 0.75

3.45 ± 0.18

143.93 ± 0.40

2.26 ± 0.80

1.72 ± 0.38

1.70 ± 0.34

P

5.83 ± 0.23

8.58 ± 0.34

1.38 ± 0.20

7.99 ± 0.87

83.99 ± 0.76

5.25 ± 0.34

110.87 ± 0.32

3.45 ± 0.23

146.35 ± 0.45

2.26 ± 0.55

1.26 ± 0.39

1.70 ± 0.39

A2 + P

5.63 ± 0.65

8.58 ± 0.56

1.34 ± 0.25

7.99 ± 0.28

79.82 ± 0.23

5.25 ± 0.53

105.36 ± 0.61

3.45 ± 0.56

139.08 ± 0.39

2.26 ± 0.29

1.6 ± 0.19

1.70 ± 0.77