Group

Inflammation of hind paw (gm)

IL-1β content

(pg/ml)

TNF-α content in rat serum (ng/l)

NO content of

rat hind paw

(μm/gm)

GSH content of

rat hind paw

(μm/gm tissue)

MDA content of rat hind paw

(μm/gm tissue)

Naiive

0.845 ± 0.058

0.537 ± 0.066

5.15 ± 0.54

19.99 ± 2.4

481 ± 37

47.6 ± 5.1

Carrageenin control

1.927 ± 0.074^*

6.32 ± 0.52^*

48.08 ± 2.5^*

68.8 ± 8.4^**

128.5 ± 18^*

179.8 ± 12^*

Tenoxicam

0.953 ± 0.036^#

0.647 ± 0.066^#

7.76 ± 1.1^#

22.74 ± 2.6^##

431 ± 43^#

52.2 ± 4.8^#

Vitamin C

______

_______

_____

____

464 ± 52^#

49.8 ± 5.2^#

Erythromycin

(200 mg/kg)

0.985 ± 0.11^#

0.669 ± 0.061^#

7.57 ± 1^#

28.9 ± 3.7^##

372 ± 52^##

72 ± 9.9^#

Erythromycin

(400 mg/kg)

0.908 ± 0.1^#

0.54 ± 0.042^#

6.62 ± 0.87^#

23.91 ± 3^##

428 ± 59^##

64.3 ± 7.8^#

Erythromycin

(800 mg/kg)

0.853 ± 0.099^#

0.3855 ± 0.027^#

5.45 ± 0.58^#

20.62 ± 2.1^##

446 ± 52^#

56.4 ± 4.2^#

Chloramphenicol

(75 mg/kg)

1.863 ± 0.17^*

5.75 ± 0.6^*

40.5 ± 3.8^*

60 ± 7.4^*

177.4 ± 24^*

135.7 ± 17^*

Chloramphenicol

(150 mg/kg)

1.636 ± 0.11^*

6.06 ± 0.7^*

44.12 ± 2.9^*

55.2 ± 5.4^*

163.8 ± 23^*

156.7 ± 12^*

Chloramphenicol

(300 mg/kg)

1.579 ± 0.16^**

6.13 ± 0.68^*

46.5 ± 4.9^*

50.9 ± 4.5^**

144.3 ± 20^*

170.4 ± 17^**